Academic Journal

Fish collagen peptides supplementation ameliorates skeletal muscle injury in high-fat diet mice associated with thyroid function recovery

التفاصيل البيبلوغرافية
العنوان: Fish collagen peptides supplementation ameliorates skeletal muscle injury in high-fat diet mice associated with thyroid function recovery
المؤلفون: Yuhui Yang, Hao Yang, Xu Tian, Wenhan Jian, Nazish Muzaffar, Guowei Le, Yanli Xie, Peng Li, Yuncong Xu
المصدر: Journal of Functional Foods, Vol 123, Iss , Pp 106612- (2024)
بيانات النشر: Elsevier, 2024.
سنة النشر: 2024
المجموعة: LCC:Nutrition. Foods and food supply
مصطلحات موضوعية: Fish collagen peptides, High-fat diet, Obesity, Skeletal muscle injury, Oxidative stress, Thyroid function, Nutrition. Foods and food supply, TX341-641
الوصف: This study aims to explore the effects of fish collagen peptides (FCP) supplementation on skeletal muscle injury in high-fat (HF) diet mice and their possible mechanisms. Experimental mice were fed a normal diet (4 % fat), HF diet (20 % fat), or FCP diet (20 % fat and 1 % FCPs) for 22 consecutive weeks. Results show that FCP supplementation improves skeletal muscle motor function and histomorphology, and lipid levels; promotes protein synthesis, and inhibits protein degradation in skeletal muscle. Moreover, FCP supplementation also improves mitochondrial biogenesis, promotes energy metabolism and ATP production. Furthermore, FCP supplementation increases antioxidant defenses in the thyroid and skeletal muscle, improves thyroid morphological structure, promotes the synthesis and secretion of thyroid hormones, and enhances the actions of thyroid hormones on its receptor organ skeletal muscle. Cumulatively, these findings indicate that FCP supplementation can alleviate skeletal muscle injury induced by an HF diet associated with thyroid function recovery.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1756-4646
Relation: http://www.sciencedirect.com/science/article/pii/S1756464624006157; https://doaj.org/toc/1756-4646
DOI: 10.1016/j.jff.2024.106612
URL الوصول: https://doaj.org/article/0da232018f364c68bd5650bbb0148d1d
رقم الانضمام: edsdoj.0da232018f364c68bd5650bbb0148d1d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17564646
DOI:10.1016/j.jff.2024.106612