Academic Journal

Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options

التفاصيل البيبلوغرافية
العنوان: Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options
المؤلفون: Nurşen Yüksel, Büşra Yılmaz Tuğan
المصدر: Türk Oftalmoloji Dergisi, Vol 53, Iss 4, Pp 247-256 (2023)
بيانات النشر: Galenos Yayinevi, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine
LCC:Ophthalmology
مصطلحات موضوعية: pseudoexfoliation, pseudoexfoliation syndrome, pseudoexfoliation glaucoma, Medicine, Ophthalmology, RE1-994
الوصف: Pseudoexfoliation syndrome (PES) is one of the most common causes of open-angle glaucoma, with a higher risk of vision loss, a higher maximum and mean intraocular pressure (IOP) at diagnosis, and a wider range of IOP fluctuation compared to primary open-angle glaucoma. Patients with this syndrome have a ten-fold higher risk of developing glaucoma than the normal population. A definite diagnosis can be made by the observation of pseudoexfoliation material (PEM) on the anterior lens surface, ciliary processes, zonules, and iris. PEM deposits on the zonules may explain the clinically observed zonular weakness and lens subluxation or dislocation. An increased incidence of cataract development is also associated with PES. There is growing evidence for systemic associations of PES with peripheral, cardiovascular, and cerebrovascular system diseases, Alzheimer’s disease, hearing loss, and increased plasma homocysteine levels. Indications for surgery are markedly more common in patients with pseudoexfoliation glaucoma than primary open-angle glaucoma. The goal of this article is to review the latest perspectives on the clinical features, therapy, and systemic associations of this clinically and biologically challenging disease.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
Turkish
تدمد: 1300-0659
2147-2661
Relation: http://www.oftalmoloji.org/archives/archive-detail/article-preview/pseudoexfoliation-glaucoma-clinical-presentation-a/61597; https://doaj.org/toc/1300-0659; https://doaj.org/toc/2147-2661
DOI: 10.4274/tjo.galenos.2023.76300
URL الوصول: https://doaj.org/article/0d5acaa7666e4027a43f84fe7e44a9eb
رقم الانضمام: edsdoj.0d5acaa7666e4027a43f84fe7e44a9eb
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:13000659
21472661
DOI:10.4274/tjo.galenos.2023.76300