Academic Journal
Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options
العنوان: | Pseudoexfoliation Glaucoma: Clinical Presentation and Therapeutic Options |
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المؤلفون: | Nurşen Yüksel, Büşra Yılmaz Tuğan |
المصدر: | Türk Oftalmoloji Dergisi, Vol 53, Iss 4, Pp 247-256 (2023) |
بيانات النشر: | Galenos Yayinevi, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Medicine LCC:Ophthalmology |
مصطلحات موضوعية: | pseudoexfoliation, pseudoexfoliation syndrome, pseudoexfoliation glaucoma, Medicine, Ophthalmology, RE1-994 |
الوصف: | Pseudoexfoliation syndrome (PES) is one of the most common causes of open-angle glaucoma, with a higher risk of vision loss, a higher maximum and mean intraocular pressure (IOP) at diagnosis, and a wider range of IOP fluctuation compared to primary open-angle glaucoma. Patients with this syndrome have a ten-fold higher risk of developing glaucoma than the normal population. A definite diagnosis can be made by the observation of pseudoexfoliation material (PEM) on the anterior lens surface, ciliary processes, zonules, and iris. PEM deposits on the zonules may explain the clinically observed zonular weakness and lens subluxation or dislocation. An increased incidence of cataract development is also associated with PES. There is growing evidence for systemic associations of PES with peripheral, cardiovascular, and cerebrovascular system diseases, Alzheimer’s disease, hearing loss, and increased plasma homocysteine levels. Indications for surgery are markedly more common in patients with pseudoexfoliation glaucoma than primary open-angle glaucoma. The goal of this article is to review the latest perspectives on the clinical features, therapy, and systemic associations of this clinically and biologically challenging disease. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English Turkish |
تدمد: | 1300-0659 2147-2661 |
Relation: | http://www.oftalmoloji.org/archives/archive-detail/article-preview/pseudoexfoliation-glaucoma-clinical-presentation-a/61597; https://doaj.org/toc/1300-0659; https://doaj.org/toc/2147-2661 |
DOI: | 10.4274/tjo.galenos.2023.76300 |
URL الوصول: | https://doaj.org/article/0d5acaa7666e4027a43f84fe7e44a9eb |
رقم الانضمام: | edsdoj.0d5acaa7666e4027a43f84fe7e44a9eb |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 13000659 21472661 |
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DOI: | 10.4274/tjo.galenos.2023.76300 |