التفاصيل البيبلوغرافية
| العنوان: |
HPV prevalence and genotype distribution among 38 056 women in Weifang, China: a cross-sectional study |
| المؤلفون: |
Mengmeng Liu, Xuguang Zhang, Lulu Guo, Wanli Sun, Xuanli Jiang |
| المصدر: |
BMJ Open, Vol 13, Iss 9 (2023) |
| بيانات النشر: |
BMJ Publishing Group, 2023. |
| سنة النشر: |
2023 |
| المجموعة: |
LCC:Medicine |
| مصطلحات موضوعية: |
Medicine |
| الوصف: |
Objectives Human papillomavirus (HPV) infection is closely associated with cervical cancer, especially the persistent infection of high-risk HPV (HR-HPV) genotypes. Therefore, investigating the HPV prevalence, age-specific, genotype distribution and the impact of the COVID-19 pandemic among large populations was essential for HPV screening and optimising vaccination.Design This was a cross-sectional study.Methods A total of 38 056 cervical epithelial cell specimens were collected in Weifang city from January 2018 to December 2022. The study was divided into seven age groups based on the age of the participants. HPV genotype testing was performed by using a commercial kit which is designed for the detection of 23 HPV genotypes.Result A total of 8998 women were infected with HPV, with an overall positive rate of 23.64% (8998/38 056). Single infection of HPV was dominant among different age groups, which accounted for 71.33% of total infections. The most prevalent genotype was HR-HPV 16 (4.33%), followed by 52, 58, 53 and 68. Low-risk HPV (LR-HPV) 42 exhibited the highest prevalence (2.19%) among six LR-HPV genotypes, representing a novel finding. There was a significant difference in the prevalence across different age groups (p |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2044-6055 |
| Relation: |
https://bmjopen.bmj.com/content/13/9/e073332.full; https://doaj.org/toc/2044-6055 |
| DOI: |
10.1136/bmjopen-2023-073332 |
| URL الوصول: |
https://doaj.org/article/0b82e9435cab4472b80f9fab08737e51 |
| رقم الانضمام: |
edsdoj.0b82e9435cab4472b80f9fab08737e51 |
| قاعدة البيانات: |
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