التفاصيل البيبلوغرافية
| العنوان: |
Molecular characterization of NDM and OXA-48-like-producing Klebsiella pneumoniae ST16 and hypervirulent ST337 clone among two patients; a case report |
| المؤلفون: |
Sarvenaz Sokhanvari, Atiyeh Bagheri, Farzad Badmasti, Hamid Solgi |
| المصدر: |
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-5 (2024) |
| بيانات النشر: |
BMC, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Infectious and parasitic diseases |
| مصطلحات موضوعية: |
Hypervirulent Klebsiella pneumonia, NDM and OXA-48-like-producing Klebsiella pneumonia, Multilocus sequence typing, VAP, UTI, Infectious and parasitic diseases, RC109-216 |
| الوصف: |
Abstract Carbapenem-resistant Klebsiella pneumoniae (CRKP) infections are a major public health problem, requiring the use of last-resort antibiotics such as colistin. However, there is concern regarding the emergence of isolates resistant to this agent. The report describes two patients with urinary tract infection (UTI) and ventilator-associated pneumonia (VAP) infection caused by CRKP strains. The first case was a 23-year-old male with UTI caused by a strain of ST16 co-harboring bla CTX-M, bla TEM, bla SHV, bla NDM, bla OXA-48-like genes. The second case was a 39-year-old woman with VAP due to hypervirulent ST337-K2 co-harboring bla SHV, bla NDM, bla OXA-48-like, iucA, rmpA2 and rmpA . The patients’ general condition improved after combination therapy with colistin (plus meropenem and rifampin, respectively) and both of them recovered and were discharged from the hospital. This study highlights the necessary prevention and control steps to prevent the further spread of CRKP strains should be a priority in our hospital. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1471-2334 |
| Relation: |
https://doaj.org/toc/1471-2334 |
| DOI: |
10.1186/s12879-024-09762-7 |
| URL الوصول: |
https://doaj.org/article/0b81cae321c3453b81eb14eeb82d2a45 |
| رقم الانضمام: |
edsdoj.0b81cae321c3453b81eb14eeb82d2a45 |
| قاعدة البيانات: |
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