التفاصيل البيبلوغرافية
| العنوان: |
The genetic mechanism of B chromosome drive in rye illuminated by chromosome-scale assembly |
| المؤلفون: |
Jianyong Chen, Jan Bartoš, Anastassia Boudichevskaia, Anna Voigt, Mark Timothy Rabanus-Wallace, Steven Dreissig, Zuzana Tulpová, Hana Šimková, Jiří Macas, Gihwan Kim, Jonas Buhl, Katharina Bürstenbinder, Frank R. Blattner, Jörg Fuchs, Thomas Schmutzer, Axel Himmelbach, Veit Schubert, Andreas Houben |
| المصدر: |
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024) |
| بيانات النشر: |
Nature Portfolio, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Science |
| مصطلحات موضوعية: |
Science |
| الوصف: |
Abstract The genomes of many plants, animals, and fungi frequently comprise dispensable B chromosomes that rely upon various chromosomal drive mechanisms to counteract the tendency of non-essential genetic elements to be purged over time. The B chromosome of rye – a model system for nearly a century – undergoes targeted nondisjunction during first pollen mitosis, favouring segregation into the generative nucleus, thus increasing their numbers over generations. However, the genetic mechanisms underlying this process are poorly understood. Here, using a newly-assembled, ~430 Mb-long rye B chromosome pseudomolecule, we identify five candidate genes whose role as trans-acting moderators of the chromosomal drive is supported by karyotyping, chromosome drive analysis and comparative RNA-seq. Among them, we identify DCR28, coding a microtubule-associated protein related to cell division, and detect this gene also in the B chromosome of Aegilops speltoides. The DCR28 gene family is neo-functionalised and serially-duplicated with 15 B chromosome-located copies that are uniquely highly expressed in the first pollen mitosis of rye. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2041-1723 |
| Relation: |
https://doaj.org/toc/2041-1723 |
| DOI: |
10.1038/s41467-024-53799-w |
| URL الوصول: |
https://doaj.org/article/c0b432de184e44efa403718628097231 |
| رقم الانضمام: |
edsdoj.0b432de184e44efa403718628097231 |
| قاعدة البيانات: |
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