التفاصيل البيبلوغرافية
| العنوان: |
Stimulating the posterior parietal cortex reduces self-reported risk-taking propensity in people with tobacco use disorder |
| المؤلفون: |
Francesca M. LoFaro, Timothy Jordan, Michael R. Apostol, Vaughn R. Steele, Anna B. Konova, Nicole Petersen |
| المصدر: |
Addiction Neuroscience, Vol 12, Iss , Pp 100160- (2024) |
| بيانات النشر: |
Elsevier, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Neurosciences. Biological psychiatry. Neuropsychiatry |
| مصطلحات موضوعية: |
Risk-taking, rTMS, Posterior parietal cortex, Smoking, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571 |
| الوصف: |
Previous research has identified a replicable role for the posterior parietal cortex (PPC) in risk behaviors, but it is unclear whether this relationship is causal. Here, we used a targeted neuromodulation protocol leveraging a single-session of 10-Hz rTMS to the PPC versus a control region in the visual cortex (V5), as well as two active comparison regions [superior frontal gyrus (SFG), dorsolateral prefrontal cortex (DLPFC)] (within-person, randomized order), to examine within-session changes in a comprehensive measure of self-reported risk-taking propensity (the Domain-Specific Risk-Taking or DOSPERT scale). Individuals with tobacco use disorder were selected as sample participants who present with clinically relevant risk-taking propensity (N = 50; 14 women, mean [SE] age=33.1 [1.04] years). Results indicated that stimulating the PPC (versus V5) resulted in trend-level reductions in self-reported risk-taking propensity (region-by-time interaction, P = 0.065). A similar pattern emerged comparing PPC stimulation to effects of stimulating either the DLPFC (P = 0.080) or SFG (P = 0.032). PPC-related reductions in risk-taking propensity were domain general and potentially driven by changes in risk perception rather than perceptions of expected benefits of risk-taking. These findings support a possible causal role of the PPC in risk behaviors that warrants further consideration for therapeutic indications in conditions like tobacco use disorder. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2772-3925 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2772392524000191; https://doaj.org/toc/2772-3925 |
| DOI: |
10.1016/j.addicn.2024.100160 |
| URL الوصول: |
https://doaj.org/article/0b11d3bedebd4a5c930a3526b4218450 |
| رقم الانضمام: |
edsdoj.0b11d3bedebd4a5c930a3526b4218450 |
| قاعدة البيانات: |
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