التفاصيل البيبلوغرافية
العنوان: |
Association of necrotizing enterocolitis with antimicrobial exposure in preterm infants |
المؤلفون: |
Xiaojing Pei, Yujun Gao, Yan Kou, Yanjie Ding, Dan Li, Peng Lei, Lili Zuo, Qiongyu Liu, Naiying Miao, Simmy Reddy, Yonghui Yu, Xuemei Sun |
المصدر: |
Frontiers in Pharmacology, Vol 13 (2022) |
بيانات النشر: |
Frontiers Media S.A., 2022. |
سنة النشر: |
2022 |
المجموعة: |
LCC:Therapeutics. Pharmacology |
مصطلحات موضوعية: |
necrotizing enterocolitis, very preterm infants, multicenter, antimicrobial exposure, case-control study, Therapeutics. Pharmacology, RM1-950 |
الوصف: |
Objective: To assess the risk of necrotizing enterocolitis (NEC) and explore the relationship between antibiotic overexposure and disease occurrence in a large prospective birth cohort.Methods: Based on a prospective birth cohort, the study collected hospitalization data of very preterm infants (VPIs) having gestational age of less than 32 weeks from January 1, 2018, to June 30, 2021 via the China Northern Neonatal Network. Infants diagnosed with NEC ≥ stage II were included in the case group, and each case was matched for GA and birth weight for the control group. Furthermore, the risk factors for NEC were determined by statistical analyses.Results: A total of 6425 VPIs were included in this study, and 167 (2.6%) of these subjects were diagnosed with NEC ≥ stage II. The study also included 984 extremely preterm infants (gestational age |
نوع الوثيقة: |
article |
وصف الملف: |
electronic resource |
اللغة: |
English |
تدمد: |
1663-9812 |
Relation: |
https://www.frontiersin.org/articles/10.3389/fphar.2022.976487/full; https://doaj.org/toc/1663-9812 |
DOI: |
10.3389/fphar.2022.976487 |
URL الوصول: |
https://doaj.org/article/09d03e8bc2c64db3a62fdadc9a897da6 |
رقم الانضمام: |
edsdoj.09d03e8bc2c64db3a62fdadc9a897da6 |
قاعدة البيانات: |
Directory of Open Access Journals |