Academic Journal

Association of necrotizing enterocolitis with antimicrobial exposure in preterm infants

التفاصيل البيبلوغرافية
العنوان: Association of necrotizing enterocolitis with antimicrobial exposure in preterm infants
المؤلفون: Xiaojing Pei, Yujun Gao, Yan Kou, Yanjie Ding, Dan Li, Peng Lei, Lili Zuo, Qiongyu Liu, Naiying Miao, Simmy Reddy, Yonghui Yu, Xuemei Sun
المصدر: Frontiers in Pharmacology, Vol 13 (2022)
بيانات النشر: Frontiers Media S.A., 2022.
سنة النشر: 2022
المجموعة: LCC:Therapeutics. Pharmacology
مصطلحات موضوعية: necrotizing enterocolitis, very preterm infants, multicenter, antimicrobial exposure, case-control study, Therapeutics. Pharmacology, RM1-950
الوصف: Objective: To assess the risk of necrotizing enterocolitis (NEC) and explore the relationship between antibiotic overexposure and disease occurrence in a large prospective birth cohort.Methods: Based on a prospective birth cohort, the study collected hospitalization data of very preterm infants (VPIs) having gestational age of less than 32 weeks from January 1, 2018, to June 30, 2021 via the China Northern Neonatal Network. Infants diagnosed with NEC ≥ stage II were included in the case group, and each case was matched for GA and birth weight for the control group. Furthermore, the risk factors for NEC were determined by statistical analyses.Results: A total of 6425 VPIs were included in this study, and 167 (2.6%) of these subjects were diagnosed with NEC ≥ stage II. The study also included 984 extremely preterm infants (gestational age
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1663-9812
Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.976487/full; https://doaj.org/toc/1663-9812
DOI: 10.3389/fphar.2022.976487
URL الوصول: https://doaj.org/article/09d03e8bc2c64db3a62fdadc9a897da6
رقم الانضمام: edsdoj.09d03e8bc2c64db3a62fdadc9a897da6
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:16639812
DOI:10.3389/fphar.2022.976487