التفاصيل البيبلوغرافية
| العنوان: |
Quantitative fragmented QRS has a good diagnostic value on myocardial fibrosis in hypertrophic obstructive cardiomyopathy based on clinical-pathological study |
| المؤلفون: |
Xuanye Bi, Chengzhi Yang, Yunhu Song, Jiansong Yuan, Jingang Cui, Fenghuan Hu, Shubin Qiao |
| المصدر: |
BMC Cardiovascular Disorders, Vol 20, Iss 1, Pp 1-9 (2020) |
| بيانات النشر: |
BMC, 2020. |
| سنة النشر: |
2020 |
| المجموعة: |
LCC:Diseases of the circulatory (Cardiovascular) system |
| مصطلحات موضوعية: |
Quantitative fragmented QRS, Myocadial fibrosis, Hypertrophic obstructive cardiomyopathy, Diseases of the circulatory (Cardiovascular) system, RC666-701 |
| الوصف: |
Abstract Background To investigate the relationship between fragmented QRS (fQRS) quantified by a new method and myocardial fibrosis (MF) and the diagnostic value of quantitative fQRS (Q-fQRS) to detect MF in hypertrophic obstructive cardiomyopathy (HOCM) patients based on histological validation. Methods We performed a retrospective study that included 69 patients with HOCM who underwent ventricular septal surgery. Nine individuals who died from accidents were studied as a control reference for the histological parameters. Septal myocardium samples were subjected to Masson’s trichrome staining to quantify the collagen volume fraction (CVF). An fQRS pattern was defined as the presence of additional R waves or RSR’, evidenced by notched R or S wave on electrocardiography (ECG). The Q-fQRS was quantified as the total amount of deflections in the QRS complex in all 12 routine ECG leads together. Cardiac magnetic resonance imaging was conducted, and late gadolinium enhancement (LGE) was measured at 2, 4, 6 and 8 standard deviations (SDs). Results Of the 69 patients, fQRS was documented in 38 (55.1%) patients, the mean number of leads with fQRS was 3.7 ± 1.6, and the mean Q-fQRS was 17 ± 7.2. Compared with HOCM patients without fQRS, HOCM patients with fQRS had a higher CVF and more LGE at 6 SD (P |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1471-2261 |
| Relation: |
http://link.springer.com/article/10.1186/s12872-020-01590-2; https://doaj.org/toc/1471-2261 |
| DOI: |
10.1186/s12872-020-01590-2 |
| URL الوصول: |
https://doaj.org/article/09397907cff14d8b9900b7e123dd3743 |
| رقم الانضمام: |
edsdoj.09397907cff14d8b9900b7e123dd3743 |
| قاعدة البيانات: |
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