Academic Journal
An Electronic Health Record-Integrated Computerized Intravenous Insulin Infusion Protocol: Clinical Outcomes and Adjustment
العنوان: | An Electronic Health Record-Integrated Computerized Intravenous Insulin Infusion Protocol: Clinical Outcomes and Adjustment |
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المؤلفون: | Sung Woon Park, Seunghyun Lee, Won Chul Cha, Kyu Yeon Hur, Jae Hyeon Kim, Moon-Kyu Lee, Sung-Min Park, Sang-Man Jin |
المصدر: | Diabetes & Metabolism Journal, Vol 44, Iss 1, Pp 56-66 (2020) |
بيانات النشر: | Korean Diabetes Association, 2020. |
سنة النشر: | 2020 |
المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
مصطلحات موضوعية: | computer simulation, electronic health records, insulin, medical records systems, computerized, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
الوصف: | BackgroundWe aimed to describe the outcome of a computerized intravenous insulin infusion (CII) protocol integrated to the electronic health record (EHR) system and to improve the CII protocol in silico using the EHR-based predictors of the outcome.MethodsClinical outcomes of the patients who underwent the CII protocol between July 2016 and February 2017 and their matched controls were evaluated. In the CII protocol group (n=91), multivariable binary logistic regression analysis models were used to determine the independent associates with a delayed response (taking ≥6.0 hours for entering a glucose range of 70 to 180 mg/dL). The CII protocol was adjusted in silico according to the EHR-based parameters obtained in the first 3 hours of CII.ResultsUse of the CII protocol was associated with fewer subjects with hypoglycemia alert values (P=0.003), earlier (P=0.002), and more stable (P=0.017) achievement of a glucose range of 70 to 180 mg/dL. Initial glucose level (P=0.001), change in glucose during the first 2 hours (P=0.026), and change in insulin infusion rate during the first 3 hours (P=0.029) were independently associated with delayed responses. Increasing the insulin infusion rate temporarily according to these parameters in silico significantly reduced delayed responses (P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2233-6079 2233-6087 |
Relation: | http://e-dmj.org/upload/pdf/dmj-44-56.pdf; https://doaj.org/toc/2233-6079; https://doaj.org/toc/2233-6087 |
DOI: | 10.4093/dmj.2018.0227 |
URL الوصول: | https://doaj.org/article/c08b25bbebfd4cda8a0eb2f90e595af0 |
رقم الانضمام: | edsdoj.08b25bbebfd4cda8a0eb2f90e595af0 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 22336079 22336087 |
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DOI: | 10.4093/dmj.2018.0227 |