Academic Journal

Advances in alternative splicing identification: deep learning and pantranscriptome

التفاصيل البيبلوغرافية
العنوان: Advances in alternative splicing identification: deep learning and pantranscriptome
المؤلفون: Fei Shen, Chenyang Hu, Xin Huang, Hao He, Deng Yang, Jirong Zhao, Xiaozeng Yang
المصدر: Frontiers in Plant Science, Vol 14 (2023)
بيانات النشر: Frontiers Media S.A., 2023.
سنة النشر: 2023
المجموعة: LCC:Plant culture
مصطلحات موضوعية: alternative splicing, RNA-seq, Iso-seq, detection algorithm, deep learning, pantranscriptome, Plant culture, SB1-1110
الوصف: In plants, alternative splicing is a crucial mechanism for regulating gene expression at the post-transcriptional level, which leads to diverse proteins by generating multiple mature mRNA isoforms and diversify the gene regulation. Due to the complexity and variability of this process, accurate identification of splicing events is a vital step in studying alternative splicing. This article presents the application of alternative splicing algorithms with or without reference genomes in plants, as well as the integration of advanced deep learning techniques for improved detection accuracy. In addition, we also discuss alternative splicing studies in the pan-genomic background and the usefulness of integrated strategies for fully profiling alternative splicing.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1664-462X
Relation: https://www.frontiersin.org/articles/10.3389/fpls.2023.1232466/full; https://doaj.org/toc/1664-462X
DOI: 10.3389/fpls.2023.1232466
URL الوصول: https://doaj.org/article/0505b13ff91c417280a443e60fc8ef47
رقم الانضمام: edsdoj.0505b13ff91c417280a443e60fc8ef47
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1664462X
DOI:10.3389/fpls.2023.1232466