التفاصيل البيبلوغرافية
| العنوان: |
Histologic and biomechanical comparison of fascia lata autograft, acellular dermal xenograft, and synthetic patch for bridging massive rotator cuff tear in a rabbit model |
| المؤلفون: |
Yuyan Na, Hao Jue, Tian Xia, Xiaoao Xue, Luyi Sun, Jun Chen, Yinghui Hua |
| المصدر: |
Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology, Vol 36, Iss , Pp 28-39 (2024) |
| بيانات النشر: |
Elsevier, 2024. |
| سنة النشر: |
2024 |
| المجموعة: |
LCC:Sports medicine |
| مصطلحات موضوعية: |
Acellular dermal matrix, Bridging repair, Fascia lata, Massive rotator cuff tears, PET, Sports medicine, RC1200-1245 |
| الوصف: |
Background: Bridging repair has emerged as a promising and reliable treatment strategy for the massive rotator cuff tears (MRCTs). However, there remains a lack of evidence on which bridging graft provides the better repair results, and a dearth of animal studies comparing bridging repairs with different grafts. The purpose of this study was to evaluate the histological and biomechanical outcomes of commonly used grafts (autologous fascia lata (FL), acellular dermal matrix graft (ADM), and polyethylene terephthalate (PET) patch). Methods: A total of 66 male New Zealand White Rabbits were used to mimic a model of unilateral chronic MRCTs. The rabbits were randomly divided into three groups: (1) FL group, which underwent bridging repair with autologous FL; (2) ADM group, which underwent bridging with ADM; and (3) PET group, which underwent bridging with PET patch. Tissue samples were collected and subjected to histological analysis using Hematoxylin and eosin, Picrosirius red, Safranin O/Fast green staining, and Immunostaining. Collagen diameter and fibril density in the regenerated tendon was analyzed with transmission electron microscopy (TEM). Additionally, biomechanical tests were performed at 6 and 12 weeks after repair. Results: The regenerated tendon successfully reattached to the footprint in all experimental groups. At 6 weeks after repair, the FL group had a significantly higher Modified Tendon Histological Evaluation (MTHE) score at the regenerated tendon than the PET group (13.2 ± 1.64 vs 9.6 ± 1.95, respectively; P = 0.038). The picrosirius red staining results showed that the FL group had a significantly higher type I collagen content than the ADM and PET groups at 6 weeks, and this difference was sustained with the PET group at 12 weeks (P |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
2214-6873 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S2214687324000074; https://doaj.org/toc/2214-6873 |
| DOI: |
10.1016/j.asmart.2024.01.007 |
| URL الوصول: |
https://doaj.org/article/0410d8fffe804a8ba99d4f670ccb7614 |
| رقم الانضمام: |
edsdoj.0410d8fffe804a8ba99d4f670ccb7614 |
| قاعدة البيانات: |
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