Academic Journal
Contrasting quiescent G0 phase with mitotic cell cycling in the mouse immune system.
| العنوان: | Contrasting quiescent G0 phase with mitotic cell cycling in the mouse immune system. |
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| المؤلفون: | Michio Tomura, Asako Sakaue-Sawano, Yoshiko Mori, Mitsuyo Takase-Utsugi, Akihiro Hata, Kenji Ohtawa, Osami Kanagawa, Atsushi Miyawaki |
| المصدر: | PLoS ONE, Vol 8, Iss 9, p e73801 (2013) |
| بيانات النشر: | Public Library of Science (PLoS), 2013. |
| سنة النشر: | 2013 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | A transgenic mouse line expressing Fucci (fluorescent ubiquitination-based cell-cycle indicator) probes allows us to monitor the cell cycle in the hematopoietic system. Two populations with high and low intensities of Fucci signals for Cdt1(30/120) accumulation were identified by FACS analysis, and these correspond to quiescent G0 and cycling G1 cells, respectively. We observed the transition of immune cells between quiescent and proliferative phases in lymphoid organs during differentiation and immune responses. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1932-6203 |
| Relation: | http://europepmc.org/articles/PMC3774768?pdf=render; https://doaj.org/toc/1932-6203 |
| DOI: | 10.1371/journal.pone.0073801 |
| URL الوصول: | https://doaj.org/article/03ee1be2b13b406585f655de3a2ecea4 |
| رقم الانضمام: | edsdoj.03ee1be2b13b406585f655de3a2ecea4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19326203 |
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| DOI: | 10.1371/journal.pone.0073801 |