Academic Journal
Herpes simplex virus ophthalmic disease induced using two different methods of mice inoculation
| العنوان: | Herpes simplex virus ophthalmic disease induced using two different methods of mice inoculation |
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| المؤلفون: | Sílvia Regina Ferreira Gonçalves Pereira, Maria Angélica A. M. Guimarães, Leonardo V. Neto, Daniel Segenreich, Rafael Brandão Varella, Vera Lucia Antunes Chagas, Fernando Portela Câmara |
| المصدر: | Brazilian Journal of Infectious Diseases, Vol 5, Iss 4, Pp 183-191 |
| بيانات النشر: | Elsevier. |
| المجموعة: | LCC:Infectious and parasitic diseases LCC:Microbiology |
| مصطلحات موضوعية: | Herpes simplex virus, ophthalmic disease, non-traumatic and traumatic inoculation, murine model, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502 |
| الوصف: | Two different procedures for inoculation of HSV on corneas of BALB/c mice were evaluated. The first was by the use of HSV suspensions directly on the corneas and the other was after corneal scarification. Animals by this later method presented greater morbidity and mortality than those of first group, suggesting that inoculation of HSV without scarification of the cornea should be the method of choice for the study of HSV ophthalmic infection. This model showed also be an efficient experimental system to testing antiviral drugs. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1678-4391 1413-8670 |
| Relation: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702001000400004&lng=en&tlng=en; https://doaj.org/toc/1678-4391 |
| DOI: | 10.1590/S1413-86702001000400004 |
| URL الوصول: | https://doaj.org/article/03a7cef6ca4f483cb31cb68c4b29aa8f |
| رقم الانضمام: | edsdoj.03a7cef6ca4f483cb31cb68c4b29aa8f |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 16784391 14138670 |
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| DOI: | 10.1590/S1413-86702001000400004 |