Academic Journal

Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition

التفاصيل البيبلوغرافية
العنوان: Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition
المؤلفون: Gautham R. Balaji, Oscar A. Aguilar, Miho Tanaka, Miguel A. Shingu-Vazquez, Zhihui Fu, Benjamin S. Gully, Lewis L. Lanier, James R. Carlyle, Jamie Rossjohn, Richard Berry
المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
بيانات النشر: Nature Portfolio, 2018.
سنة النشر: 2018
المجموعة: LCC:Science
مصطلحات موضوعية: Science
الوصف: Natural killer (NK) cells eliminate damaged cells, but spare healthy ones by recognizing their expressed ligands via NK inhibitory receptors. Here the authors solve the structure of an NK inhibitory receptor, NKR-P1B, bound to its ligand, Clr-b, with further data suggesting a weak interaction and informing on the basis of missing-self recognition.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2041-1723
Relation: https://doaj.org/toc/2041-1723
DOI: 10.1038/s41467-018-06989-2
URL الوصول: https://doaj.org/article/d0281b6f4ebc43a183d59a0c42bc49bc
رقم الانضمام: edsdoj.0281b6f4ebc43a183d59a0c42bc49bc
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:20411723
DOI:10.1038/s41467-018-06989-2