Academic Journal
Contribution of cardio-vascular risk factors to depressive status in the PREDIMED-PLUS Trial. A cross-sectional and a 2-year longitudinal study.
| العنوان: | Contribution of cardio-vascular risk factors to depressive status in the PREDIMED-PLUS Trial. A cross-sectional and a 2-year longitudinal study. |
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| المؤلفون: | Sandra Martín-Peláez, Lluis Serra-Majem, Naomi Cano-Ibáñez, Miguel Ángel Martínez-González, Jordi Salas-Salvadó, Dolores Corella, Camille Lassale, Jose Alfredo Martínez, Ángel M Alonso-Gómez, Julia Wärnberg, Jesús Vioque, Dora Romaguera, José López-Miranda, Ramón Estruch, Francisco J Tinahones, José Lapetra, Fernando Fernández-Aranda, Aurora Bueno-Cavanillas, Josep A Tur, Vicente Martín, Xavier Pintó, Miguel Delgado-Rodríguez, Pilar Matía, Josep Vidal, Clotilde Vázquez, Lidia Daimiel, Emili Ros, Estefanía Toledo, Stephanie K Nishi, Jose V Sorli, Mireia Malcampo, M Ángeles Zulet, Anaí Moreno-Rodríguez, Raquel Cueto-Galán, Diego Vivancos-Aparicio, Antoni Colom, Antonio García-Ríos, Rosa Casas, M Rosa Bernal-López, Jose Manuel Santos-Lozano, Zenaida Vázquez, Carlos Gómez-Martínez, Carolina Ortega-Azorín, Jose Luís Del Val, Itziar Abete, Amaia Goikoetxea-Bahon, Elena Pascual, Nerea Becerra-Tomás, Juan J Chillarón, Almudena Sánchez-Villegas |
| المصدر: | PLoS ONE, Vol 17, Iss 4, p e0265079 (2022) |
| بيانات النشر: | Public Library of Science (PLoS), 2022. |
| سنة النشر: | 2022 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | BackgroundCardio-vascular disease and depression are thought to be closely related, due to shared risk factors. The aim of the study was to determine the association between cardio-vascular risk (CVR) factors and depressive status in a population (55-75 years) with metabolic syndrome (MetS) from the PREDIMED-Plus trial.Methods and findingsParticipants were classified into three groups of CVR according to the Framingham-based REGICOR function: (1) low (LR), (2) medium (MR) or (3) high/very high (HR). The Beck Depression Inventory-II (BDI-II) was used to assess depressive symptoms at baseline and after 2 years. The association between CVR and depressive status at baseline (n = 6545), and their changes after 2 years (n = 4566) were evaluated through multivariable regression models (logistic and linear models). HR women showed higher odds of depressive status than LR [OR (95% CI) = 1.78 (1.26, 2.50)]. MR and HR participants with total cholesterol ConclusionsImproving cardiovascular health could prevent the onset of depression in the elderly. Diabetes and total cholesterol in individuals at high CVR, may play a specific role in the precise response. International Standard Randomized Controlled Trial (ISRCTN89898870). |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1932-6203 |
| Relation: | https://doaj.org/toc/1932-6203 |
| DOI: | 10.1371/journal.pone.0265079 |
| URL الوصول: | https://doaj.org/article/02243d3a486045c9bec3e20599010d39 |
| رقم الانضمام: | edsdoj.02243d3a486045c9bec3e20599010d39 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19326203 |
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| DOI: | 10.1371/journal.pone.0265079 |