التفاصيل البيبلوغرافية
| العنوان: |
Coumarin derivatives as promising antibacterial agent(s) |
| المؤلفون: |
Chita Ranjan Sahoo, Jyotirmaya Sahoo, Monalisa Mahapatra, Debananda Lenka, Pratap Kumar Sahu, Budheswar Dehury, Rabindra Nath Padhy, Sudhir Kumar Paidesetty |
| المصدر: |
Arabian Journal of Chemistry, Vol 14, Iss 2, Pp 102922- (2021) |
| بيانات النشر: |
Elsevier, 2021. |
| سنة النشر: |
2021 |
| المجموعة: |
LCC:Chemistry |
| مصطلحات موضوعية: |
Coumarin, Semi-synthesis, Antibacterial, Structural-activity-relationship, Chemistry, QD1-999 |
| الوصف: |
Nowadays, bacterial infections epitomize significant health threats globally with an increased morbidity and mortality. Most contemporary antibacterial agents are resisted by pathogenic bacteria - the multidrug resistant (MDR) bacterial strains arising from cross resistances operative in natural bacterial consortia inside human body and in environments. Consequently, the development of newer potential drug candidate(s) is required against the broad spectrum of MDR bacteria. Indeed, the phytochemical coumarin and its derivatives had been reported with broad biological inhibitory properties, including antibacterial activities. In this review, several methods of synthetic strategies of coumarin derivatives as antibacterials were considered with individual schematic compounds by structure-activity relationship (SAR) studies as essential corollaries. Overall, substituents at positions C-3 and C-4 of coumarin are coveted for the development of newer antibacterial agents. |
| نوع الوثيقة: |
article |
| وصف الملف: |
electronic resource |
| اللغة: |
English |
| تدمد: |
1878-5352 |
| Relation: |
http://www.sciencedirect.com/science/article/pii/S1878535220304834; https://doaj.org/toc/1878-5352 |
| DOI: |
10.1016/j.arabjc.2020.102922 |
| URL الوصول: |
https://doaj.org/article/00e75562920d4ede82965f047cc6a5cd |
| رقم الانضمام: |
edsdoj.00e75562920d4ede82965f047cc6a5cd |
| قاعدة البيانات: |
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