Academic Journal
Comparison Between Magnetic Resonance Imaging and Computed Tomography in the Detection and Volumetric Assessment of Lung Nodules: A Prospective Study
| العنوان: | Comparison Between Magnetic Resonance Imaging and Computed Tomography in the Detection and Volumetric Assessment of Lung Nodules: A Prospective Study |
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| المؤلفون: | Darçot, Emeline, Jreige, Mario, Rotzinger, David C., Gidoin Tuyet Van, Stacey, Casutt, Alessio, Delacoste, Jean, Simons, Julien, Long, Olivier, Buela, Flore, Ledoux, Jean-Baptiste, Prior, John O., Lovis, Alban, Beigelman-Aubry, Catherine |
| المساهمون: | Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Fondation Leenaards |
| المصدر: | Frontiers in Medicine ; volume 9 ; ISSN 2296-858X |
| بيانات النشر: | Frontiers Media SA |
| سنة النشر: | 2022 |
| المجموعة: | Frontiers (Publisher - via CrossRef) |
| الوصف: | Rationale and Objectives Computed tomography (CT) lung nodule assessment is routinely performed and appears very promising for lung cancer screening. However, the radiation exposure through time remains a concern. With the overall goal of an optimal management of indeterminate lung nodules, the objective of this prospective study was therefore to evaluate the potential of optimized ultra-short echo time (UTE) MRI for lung nodule detection and volumetric assessment. Materials and Methods Eight (54.9 ± 13.2 years) patients with at least 1 non-calcified nodule ≥4 mm were included. UTE under high-frequency non-invasive ventilation (UTE-HF-NIV) and in free-breathing at tidal volume (UTE-FB) were investigated along with volumetric interpolated breath-hold examination at full inspiration (VIBE-BH). Three experienced readers assessed the detection rate of nodules ≥4 mm and ≥6 mm, and reported their location, 2D-measurements and solid/subsolid nature. Volumes were measured by two experienced readers. Subsequently, two readers assessed the detection and volume measurements of lung nodules ≥4mm in gold-standard CT images with soft and lung kernel reconstructions. Volumetry was performed with lesion management software (Carestream, Rochester, New York, USA). Results UTE-HF-NIV provided the highest detection rate for nodules ≥4 mm ( n = 66) and ≥6 mm ( n = 32) (35 and 50%, respectively). No dependencies were found between nodule detection and their location in the lung with UTE-HF-NIV ( p > 0.4), such a dependency was observed for two readers with VIBE-BH ( p = 0.002 and 0.03). Dependencies between the nodule's detection and their size were noticed among readers and techniques ( p < 0.02). When comparing nodule volume measurements, an excellent concordance was observed between CT and UTE-HF-NIV, with an overestimation of 13.2% by UTE-HF-NIV, <25%-threshold used for nodule's growth, conversely to VIBE-BH that overestimated the nodule volume by 28.8%. Conclusion UTE-HF-NIV is not ready to replace low-dose ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| DOI: | 10.3389/fmed.2022.858731 |
| DOI: | 10.3389/fmed.2022.858731/full |
| الاتاحة: | http://dx.doi.org/10.3389/fmed.2022.858731 https://www.frontiersin.org/articles/10.3389/fmed.2022.858731/full |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.FFE550E4 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3389/fmed.2022.858731 |
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