Academic Journal
Nephrotoxicity of uranium: pathophysiological, diagnostic and therapeutic perspectives
| العنوان: | Nephrotoxicity of uranium: pathophysiological, diagnostic and therapeutic perspectives |
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| المؤلفون: | Vicente-Vicente, L, Quiros, Y, Pérez-Barriocanal, F, López-Novoa, JM, López-Hernández, FJ, Morales, AI |
| بيانات النشر: | Oxford University Press |
| سنة النشر: | 2010 |
| المجموعة: | HighWire Press (Stanford University) |
| مصطلحات موضوعية: | Review |
| الوصف: | As in the case of other heavy metals, a considerable body of evidence suggests that overexposure to uranium may cause pathological alterations to the kidneys in both humans and animals. In the present work our aim is to analyze the available data from a critical perspective that should provide a view of the real danger of the nephrotoxicity of this metal for human beings. A further aim is to elaborate a comparative compilation of the renal pathophysiological data obtained in humans and experimental animals with a view to gaining more insight into our knowledge of the mechanisms of action and renal damage. Finally, we address the existing perspectives for the improvement of diagnostic methods and the treatment of intoxications by uranium, performing an integrated analysis of all these aspects. |
| نوع الوثيقة: | text |
| وصف الملف: | text/html |
| اللغة: | English |
| Relation: | http://toxsci.oxfordjournals.org/cgi/content/short/kfq178v1; http://dx.doi.org/10.1093/toxsci/kfq178 |
| DOI: | 10.1093/toxsci/kfq178 |
| الاتاحة: | http://toxsci.oxfordjournals.org/cgi/content/short/kfq178v1 https://doi.org/10.1093/toxsci/kfq178 |
| Rights: | Copyright (C) 2010, Society of Toxicology |
| رقم الانضمام: | edsbas.FFDF6B12 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/toxsci/kfq178 |
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