Academic Journal
Basaloid squamous cell carcinoma of the larynx: 16 years of experience at the otorhinolaryngology department of IPO-LFG ; Carcinoma basalóide escamoso da laringe: Experiência de 16 anos do serviço de ORL do IPO-LFG
| العنوان: | Basaloid squamous cell carcinoma of the larynx: 16 years of experience at the otorhinolaryngology department of IPO-LFG ; Carcinoma basalóide escamoso da laringe: Experiência de 16 anos do serviço de ORL do IPO-LFG |
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| المؤلفون: | O'Neill Mendes, Nuno, Serras, Daniela, Seixas, João, Oliveira, Mafalda, Cabeçadas, José, Ferreira, Lígia, Montalvão, Pedro, Magalhães, Miguel |
| المصدر: | Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 60 No. 1 (2022): March; 11-14 ; Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 60 Núm. 1 (2022): Março; 11-14 ; Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; v. 60 n. 1 (2022): Março; 11-14 ; 2184-6499 |
| بيانات النشر: | Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Carcinoma basalóide escamoso, Laringe, Oncologia, Basaloid squamous cell cancer, Larynx, Oncology |
| الوصف: | Objectives: Identify prognostic factors of basaloid squamous cell carcinoma of the larynx (BSCCL); evaluate survival according to staging, sublocalization and treament. Study design: Retrospective Material & methods: Cases of BSCCL at IPO-LFG(2003-2019) were identified. Sociodemographic data, staging and treatment were registered. Overall survival(OS) and disease free survival(DFS) were calculated. We used qui-square test(categorical variables), T test(continuous variable) and Kaplan-Meier method(survival comparison). Results and Conclusions: 43 individuals(mean age: 59,7 years; 97,7% males). Staging: a) local: T1 (7%), T2 (18,6%), T3 (27,9%), T4a (46,5%); b) regional: N+(60,5%); c) distance: M0 (95,3%). Localization: supraglottis (58,1%); glottis (25,6%); transglottic (16,3%). 95,3% treated with curative intent, of those, 95,2% underwent surgery(70,7% total laryngectomy; 17,1% partial supraglottic laryngectomy; 7,3% cordectomy); 2,4% RT; 2,4% CRT. 87,2% of operated underwent bilateral neck dissection. 92,3% of operated underwent adjuvant CRT/RT. DFS at 2 years was similar for T1/T2 (63,6%) and T3/T4a (63,3%). Individuals N0 at presentation showed DFS at 2 years (87,5%) > N+(48%); p=0,017. DFS at 2 years in supraglottic tumours (52,0%) was inferior to glottic (90,9%); p=0,031. BSCCL is frequently diagnosed in advanced stages. Supraglottic localization and N+ neck are the main bad prognosis factors. ; Objetivos: Identificar fatores prognósticos do carcinoma basalóide escamoso da laringe (CBEL); avaliar a sobrevida de acordo com estadio, sublocalização e tratamento. Desenho do estudo: Retrospetivo Material e métodos: Identificaram-se os CBEL no IPO-LFG (2003-2019). Registaram-se dados sociodemográficos, estadiamento e tratamento. Determinou-se sobrevida global (SG) e livre de doença (SLD). Utilizou-se o Teste qui-quadrado (variáveis categóricas), teste T (variáveis contínuas) e método Kaplan-Meier (comparar sobrevidas). Resultados e Conclusões: 43 indivíduos (Idade média:59,7anos; ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | Portuguese English |
| Relation: | https://www.journalsporl.com/index.php/sporl/article/view/964/781; https://www.journalsporl.com/index.php/sporl/article/view/964/782; https://www.journalsporl.com/index.php/sporl/article/view/964 |
| الاتاحة: | https://www.journalsporl.com/index.php/sporl/article/view/964 |
| Rights: | Direitos de Autor (c) 2022 Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço ; https://creativecommons.org/licenses/by-sa/4.0 |
| رقم الانضمام: | edsbas.FEBED887 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |