Academic Journal
Proposing Kluyvera georgiana as the Origin of the Plasmid-Mediated Resistance Gene fosA4
| العنوان: | Proposing Kluyvera georgiana as the Origin of the Plasmid-Mediated Resistance Gene fosA4 |
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| المؤلفون: | Rodriguez, Maria Margarita, Ghiglione, Barbara, Power, Pablo, Naas, Thierry, Gutkind, Gabriel |
| المساهمون: | Joint Programme Initiative on Antimicrobial Resistance, MINCyT | Agencia Nacional de Promoción Científica y Tecnológica |
| المصدر: | Antimicrobial Agents and Chemotherapy ; volume 62, issue 8 ; ISSN 0066-4804 1098-6596 |
| بيانات النشر: | American Society for Microbiology |
| سنة النشر: | 2018 |
| الوصف: | A putative fosA gene in Kluyvera georgiana 14751 showed 99% nucleotide identity with plasmid-encoded fosA4 . Due to a single-nucleotide insertion translating to a truncated protein, K. georgiana 14751 fosA does not confer fosfomycin resistance. However, analysis of another genome deposit ( Kluyvera ascorbata WCH1410) that could be recategorized as K. georgiana after phylogenetic analysis revealed a fosA gene 100% identical to the plasmid-borne fosA4 gene. We suggest that Kluyvera georgiana represents the most probable origin of fosA4 . |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1128/aac.00710-18 |
| DOI: | 10.1128/AAC.00710-18 |
| الاتاحة: | http://dx.doi.org/10.1128/aac.00710-18 https://journals.asm.org/doi/pdf/10.1128/AAC.00710-18 |
| Rights: | https://journals.asm.org/non-commercial-tdm-license |
| رقم الانضمام: | edsbas.FE1C871B |
| قاعدة البيانات: | BASE |
| DOI: | 10.1128/aac.00710-18 |
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