Academic Journal
Robotic Surgery in Pediatric Oncology: Lessons Learned from the First 100 Tumors — A Nationwide Experience
| العنوان: | Robotic Surgery in Pediatric Oncology: Lessons Learned from the First 100 Tumors — A Nationwide Experience |
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| المؤلفون: | Blanc, Thomas, Meignan, Pierre, Vinit, Nicolas, Ballouhey, Quentin, Pio, Luca, Capito, Carmen, Harte, Caroline, Vatta, Fabrizio, Galmiche-Rolland, Louise, Minard, Véronique, Orbach, Daniel, Berteloot, Laureline, Muller, Cécile, Kohaut, Jules, Broch, Aline, Braik, Karim, Binet, Aurélien, Heloury, Yves, Fourcade, Laurent, Lardy, Hubert, Sarnacki, Sabine |
| المساهمون: | Écologie et biologie des interactions (EBI), Université de Poitiers-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | ISSN: 1068-9265. |
| بيانات النشر: | HAL CCSD Springer Verlag |
| سنة النشر: | 2021 |
| المجموعة: | Université de Poitiers: Publications de nos chercheurs.ses (HAL) |
| مصطلحات موضوعية: | MESH: Adolescent, MESH: Child, Preschool, MESH: Female, MESH: Humans, MESH: Kidney Neoplasms, MESH: Medical Oncology, MESH: Postoperative Complications, MESH: Robotic Surgical Procedures, MESH: Wilms Tumor, [SDV]Life Sciences [q-bio] |
| الوصف: | International audience ; Background While robotics has become commonplace in adult oncology, it remains rare in pediatric oncology due to the rarity of childhood cancers. We present the results of a large nationwide experience with robotic oncology, with the aim of providing practical and feasible guidelines for child selection. Methods This was a prospective analysis performed over a period of 4 years. Treatment was delivered according to the Société Internationale d’Oncologie Pédiatrique/International Society of Paediatric Oncology Europe Neuroblastoma Group (SIOP/SIOPEN) protocols. Indications were approved by a certified tumor board. Results Overall, 100 tumors were resected during 93 procedures (abdomen, 67%; thorax, 17%; pelvis, 10%; retroperitoneum, 6%) in 89 children (56 girls). The median age at surgery was 8.2 years (range 3.6–13); 19 children (21%) harbored germinal genetic alterations predisposing to cancer. No intraoperative tumor ruptures occurred. Seven conversions (8%) to an open approach were performed. Neuroblastic tumors (n = 31) comprised the main group (18 neuroblastomas, 4 ganglioneuroblastomas, 9 ganglioneuromas) and renal tumors comprised the second largest group (n = 24, including 20 Wilms’ tumors). The remaining 45 tumors included neuroendocrine (n = 12), adrenal (n = 9), germ-cell (n = 7), pancreatic (n = 4), thymic (n = 4), inflammatory myofibroblastic (n = 4), and different rare tumors (n = 5). Overall, 51 tumors were malignant, 2 were borderline, and 47 were benign. The median hospital stay was 3 days (2–4), and five postoperative complications occurred within the first 30 days. During a median follow-up of 2.4 years, one child (Wilms’ tumor) presented with pleural recurrence. One girl with Wilms’ tumor died of central nervous system metastasis. Conclusions Robotic surgery for pediatric tumors is a safe option in highly selected cases. Indications should be discussed by tumor boards to avoid widespread and uncontrolled application. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/34523002; hal-04403560; https://hal.science/hal-04403560; PUBMED: 34523002 |
| DOI: | 10.1245/s10434-021-10777-6 |
| الاتاحة: | https://hal.science/hal-04403560 https://doi.org/10.1245/s10434-021-10777-6 |
| رقم الانضمام: | edsbas.FD947F58 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1245/s10434-021-10777-6 |
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