Academic Journal
ILC3 deficiency and generalized ILC abnormalities in DOCK8-deficient patients
| العنوان: | ILC3 deficiency and generalized ILC abnormalities in DOCK8-deficient patients |
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| المؤلفون: | Azizoglu, Zehra Busra, Nain, Ercan, Okus, Fatma Zehra, Cansever, Murat, Erdem, Serife, Karakukcu, MUSA, Dönmez Altuntas, Hamiyet, Unal, Ekrem, Patiroglu, Turkan, Baris, Safa, Keles, Sevgi, Chatila, Talal A., Ozen, Ahmet, Oukka, Mohamed, Canatan, Halit, Karasu, Gulsun, Uygun, Vedat, Guner, Sukru N., Reisli, Ismail, Artac, Hasibe, Kaya, Aysenur, Cipe, Funda, Metin, Ayse, Kiykim, Ayca, Karakoc Aydiner, Elif, Topal, Erdem, Arikan Ayyildiz, Zeynep, Aksu, Guzide, Devecioglu, Omer, Ozcan, Alper, Haliloglu, Yesim, Eken, Ahmet |
| سنة النشر: | 2020 |
| المجموعة: | Erciyes University Research Information System |
| الوصف: | BackgroundDedicator of cytokinesis 8 (DOCK8) deficiency is the main cause of the autosomal recessive hyper-IgE syndrome (HIES). We previously reported the selective loss of group 3 innate lymphoid cell (ILC) number and function in a Dock8-deficient mouse model. In this study, we sought to test whether DOCK8 is required for the function and maintenance of ILC subsets in humans. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | acdd8a8a-a957-4e1f-817b-b5d80492f7f5; https://avesis.erciyes.edu.tr/publication/details/acdd8a8a-a957-4e1f-817b-b5d80492f7f5/oai |
| DOI: | 10.1111/all.14081 |
| الاتاحة: | https://doi.org/10.1111/all.14081 https://avesis.erciyes.edu.tr/publication/details/acdd8a8a-a957-4e1f-817b-b5d80492f7f5/oai |
| Rights: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.FD85DB0C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/all.14081 |
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