التفاصيل البيبلوغرافية
| العنوان: |
Relationship between hair cortisol concentrations and cognitive functioning in adolescents with ADHD |
| المؤلفون: |
Llorens, Marta, Barba, Maria, Torralbas Ortega, Jordi, Nadal i Alemany, Roser, Armario Garcia, Antonio, Gagliano, Humberto Antonio, Urraca Camps, Lara, Pujol, Susana, Montalvo Aguirrezabala, Itziar, Gracia Liso, Rebeca, Polo, Diana, Gonzalez Riesco, Laura, MatalÃ, Josep LluÃs, Palao, Diego, PÃ mias Massana, Montserrat, Labad, Javier |
| سنة النشر: |
2023 |
| المجموعة: |
Universitat Autònoma de Barcelona: Dipòsit Digital de Documents de la UAB |
| مصطلحات موضوعية: |
Cortisol, Stress, ADHD, Cognition, Childhood trauma, Sex, TDAH, Cognición, Trauma infantil, Sexo |
| الوصف: |
This research was supported by the CIBER -Consorcio Centro de Investigación Biomédica en Red- (CB029), Instituto de Salud Carlos III, and Spanish Ministry of Science and Innovation. ; Background: Our study aimed to explore whether the hair cortisol concentration (HCC), a measure of long-term cortisol output, is associated with poorer cognitive functioning in adolescents with attention deficit and hyperactivity disorder (ADHD). We further aimed to test the potential moderating effects of sex and childhood maltreatment. Methods: In this cross-sectional study, fifty-three adolescents with ADHD were studied. The ADHD Rating Scale (ADHD-RS) and Childhood Trauma Questionnaire (CTQ) were administered. Seven cognitive tasks from the Cambridge Neuropsychological Test Automated Battery (CANTAB) were administered, and two cognitive factors (attention and memory and executive functioning) were identified by confirmatory factor analysis. A 3-cm hair sample from the posterior vertex region of the head was obtained. HCCs were determined by a high-sensitivity enzyme immunoassay kit. Multiple linear regression analyses were used to explore the association between HCCs and either cognitive performance or ADHD severity while adjusting for sex, childhood maltreatment and the ADHD-RS total score. Results: Sex moderated the relationship between HCCs and attention/memory confirmatory factor analysis (CFA) scores, with better performance in boys with higher HCCs. HCCs were not associated with executive functioning or ADHD symptoms. Childhood maltreatment was associated with inattention symptoms in adolescents with ADHD. Conclusions: Our study suggests that HCCs are positively associated with attention and memory performance in adolescents with ADHD, with a moderating effect of sex (the relationship is strongest in boys). |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
Spanish; Castilian |
| تدمد: |
20008066 |
| Relation: |
Agència de Gestió d'Ajuts Universitaris i de Recerca 2017/SGR-1412; European Journal of Psychotraumatology; Vol. 14 Núm. 2 (2023), art. 2281752; https://ddd.uab.cat/record/288463; urn:10.1080/20008066.2023.2281752; urn:oai:ddd.uab.cat:288463; urn:scopus_id:85177549742; urn:articleid:20008066v14n2p2281752; urn:oai:egreta.uab.cat:publications/5af8d0cf-dff5-44ba-a160-195961f94e74; urn:pmid:38154075; urn:pmc-uid:10990442; urn:pmcid:PMC10990442; urn:oai:pubmedcentral.nih.gov:10990442 |
| الاتاحة: |
https://ddd.uab.cat/record/288463 |
| Rights: |
open access ; Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, sempre que no sigui amb finalitats comercials, i sempre que es reconegui l'autoria de l'obra original. ; https://creativecommons.org/licenses/by-nc/4.0/ |
| رقم الانضمام: |
edsbas.FD2AE437 |
| قاعدة البيانات: |
BASE |
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