The Relationship between Hepatic Steatosis, inflammation and insulin Resistance in type 2 Diabetes with Metabolic Imbalance

التفاصيل البيبلوغرافية
العنوان:	The Relationship between Hepatic Steatosis, inflammation and insulin Resistance in type 2 Diabetes with Metabolic Imbalance
المؤلفون:	Grigorescu, Elena-Daniela, Floria, Mariana, Lăcătușu, Cristina Mihaela, Mircea-Mihai, Bogdan, Creţu, Ioana, Popa, Alina Delia, Onofriescu, Alina, Jaba, Irina M., Șorodoc, Victoriţa, Ceasovschih, Alexandr, Șorodoc, Laurenţiu
المصدر:	Internal Medicine ; volume 16, issue 4, page 13-25 ; ISSN 1220-5818
بيانات النشر:	Walter de Gruyter GmbH
سنة النشر:	2019
الوصف:	Aim. Non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) are in a bidirectional relationship. This prospective study focused on associations between parameters common to the pathogenesis of insulin resistance, inflammation and hepatic steatosis in T2DM patients with metabolic imbalance. Methods. We used clinical data, insulin resistance and inflammation indices, and hepatic steatosis markers from 120 patients. Results. The patients (44% men, mean age 58) had a mean body mass index (BMI) of 32 kg/m 2 and mean T2DM history of 6 years. With exceptions, significant correlations were found between metabolic, inflammatory and hepatic parameters. Conclusions. In T2DM patients with poor glycemic control, hepatic steatosis correlates significantly with insulin resistance and inflammation. Increased prevalence and poor prognosis of these diseases together justify the need for NAFLD screening of diabetic patients.
نوع الوثيقة:	article in journal/newspaper
اللغة:	English
DOI:	10.2478/inmed-2019-0073
الاتاحة:	http://dx.doi.org/10.2478/inmed-2019-0073 https://content.sciendo.com/view/journals/inmed/16/4/article-p13.xml https://www.sciendo.com/pdf/10.2478/inmed-2019-0073
Rights:	http://creativecommons.org/licenses/by-nc-nd/3.0
رقم الانضمام:	edsbas.FB4DDA1E
قاعدة البيانات:	BASE

View record in BASE

كن أول من يترك تعليقا!