Academic Journal
The Relationship between Hepatic Steatosis, inflammation and insulin Resistance in type 2 Diabetes with Metabolic Imbalance
| العنوان: | The Relationship between Hepatic Steatosis, inflammation and insulin Resistance in type 2 Diabetes with Metabolic Imbalance |
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| المؤلفون: | Grigorescu, Elena-Daniela, Floria, Mariana, Lăcătușu, Cristina Mihaela, Mircea-Mihai, Bogdan, Creţu, Ioana, Popa, Alina Delia, Onofriescu, Alina, Jaba, Irina M., Șorodoc, Victoriţa, Ceasovschih, Alexandr, Șorodoc, Laurenţiu |
| المصدر: | Internal Medicine ; volume 16, issue 4, page 13-25 ; ISSN 1220-5818 |
| بيانات النشر: | Walter de Gruyter GmbH |
| سنة النشر: | 2019 |
| الوصف: | Aim. Non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) are in a bidirectional relationship. This prospective study focused on associations between parameters common to the pathogenesis of insulin resistance, inflammation and hepatic steatosis in T2DM patients with metabolic imbalance. Methods. We used clinical data, insulin resistance and inflammation indices, and hepatic steatosis markers from 120 patients. Results. The patients (44% men, mean age 58) had a mean body mass index (BMI) of 32 kg/m 2 and mean T2DM history of 6 years. With exceptions, significant correlations were found between metabolic, inflammatory and hepatic parameters. Conclusions. In T2DM patients with poor glycemic control, hepatic steatosis correlates significantly with insulin resistance and inflammation. Increased prevalence and poor prognosis of these diseases together justify the need for NAFLD screening of diabetic patients. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.2478/inmed-2019-0073 |
| الاتاحة: | http://dx.doi.org/10.2478/inmed-2019-0073 https://content.sciendo.com/view/journals/inmed/16/4/article-p13.xml https://www.sciendo.com/pdf/10.2478/inmed-2019-0073 |
| Rights: | http://creativecommons.org/licenses/by-nc-nd/3.0 |
| رقم الانضمام: | edsbas.FB4DDA1E |
| قاعدة البيانات: | BASE |
| DOI: | 10.2478/inmed-2019-0073 |
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