Academic Journal

Application of artificial neural network for the mechano-bactericidal effect of bioinspired nanopatterned surfaces

التفاصيل البيبلوغرافية
العنوان: Application of artificial neural network for the mechano-bactericidal effect of bioinspired nanopatterned surfaces
المؤلفون: Yaylacı, Ecren Uzun
المساهمون: RTEÜ, Yaylacı, Ecren Uzun
بيانات النشر: Springer
سنة النشر: 2024
مصطلحات موضوعية: Artificial neural network, Mechano-bactericidal, Nano-patterned surface
الوصف: This study aimed to calculate the effect of nanopatterns’ peak sharpness, width, and spacing parameters on P. aeruginosa and S. aureus cell walls by artificial neural network and finite element analysis. Elastic and creep deformation models of bacteria were developed in silico. Maximum deformation, maximum stress, and maximum strain values of the cell walls were calculated. According to the results, while the spacing of the nanopatterns is constant, it was determined that when their peaks were sharpened and their width decreased, maximum deformation, maximum stress, and maximum strain affecting the cell walls of both bacteria increased. When sharpness and width of the nano-patterns are kept constant and the spacing is increased, maximum deformation, maximum stress, and maximum strain in P. aeruginosa cell walls increase, but a decrease in S. aureus was observed. This study proves that changes in the geometric structures of nanopatterned surfaces can show different effects on different bacteria.
نوع الوثيقة: article in journal/newspaper
وصف الملف: application/pdf
اللغة: English
Relation: European Biophysics Journal; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; https://hdl.handle.net/11436/9615
DOI: 10.1007/s00249-024-01723-x
الاتاحة: https://hdl.handle.net/11436/9615
https://doi.org/10.1007/s00249-024-01723-x
Rights: info:eu-repo/semantics/closedAccess
رقم الانضمام: edsbas.FACBB532
قاعدة البيانات: BASE
الوصف
DOI:10.1007/s00249-024-01723-x