Academic Journal
Mouse models of epithelial ovarian cancer for preclinical studies
| العنوان: | Mouse models of epithelial ovarian cancer for preclinical studies |
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| المؤلفون: | Sergey Karakashev, Ru-Gang Zhang |
| المصدر: | Zoological Research, Vol 42, Iss 2, Pp 153-160 (2021) |
| بيانات النشر: | Science Press, PR China |
| سنة النشر: | 2021 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | epithelial ovarian cancer, patient-derived xenografts, orthotopic mouse model, subcutaneous mouse model, intraperitoneal mouse model, syngeneic mouse model, genetic engineered mouse model, Zoology, QL1-991 |
| الوصف: | Epithelial ovarian cancer (EOC) is the leading cause of gynecological cancer-related mortality in the developed world. EOC is a heterogeneous disease represented by several histological and molecular subtypes. Therefore, exploration of relevant preclinical animal models that consider the heterogenic nature of EOC is of great importance for the development of novel therapeutic strategies that can be translated clinically to combat this devastating disease. In this review, we discuss recent progress in the development of preclinical mouse models for EOC study as well as their advantages and limitations. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2095-8137 |
| Relation: | http://www.zoores.ac.cn/EN/10.24272/j.issn.2095-8137.2020.382; https://doaj.org/toc/2095-8137; https://doaj.org/article/1cf6d5da796d4f77a53f624c0a2d21d2 |
| DOI: | 10.24272/j.issn.2095-8137.2020.382 |
| الاتاحة: | https://doi.org/10.24272/j.issn.2095-8137.2020.382 https://doaj.org/article/1cf6d5da796d4f77a53f624c0a2d21d2 |
| رقم الانضمام: | edsbas.FA12BBAD |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 20958137 |
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| DOI: | 10.24272/j.issn.2095-8137.2020.382 |