التفاصيل البيبلوغرافية
| العنوان: |
Role of Akkermansia in Human Diseases: From Causation to Therapeutic Properties |
| المؤلفون: |
Antonio Pellegrino, Gaetano Coppola, Francesco Santopaolo, Antonio Gasbarrini, Francesca Romana Ponziani |
| المصدر: |
Nutrients; Volume 15; Issue 8; Pages: 1815 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2023 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
Akkermansia muciniphila, gut, IBD, insulin sensitivity, atherosclerosis, cancer therapy |
| جغرافية الموضوع: |
agris |
| الوصف: |
The gut microbiota plays a critical role in the modulation of host metabolism and immune response, and its impairment has been implicated in many gastrointestinal and extraintestinal diseases. Current evidence shows the well-documented role of A. muciniphila in maintaining the integrity of the intestinal barrier, modulating the host immune response, and improving several metabolic pathways, making it a key element in the pathogenesis of several human diseases. In this scenario, A. muciniphila is the most promising next-generation probiotic and one of the first microbial species suitable for specific clinical use when compared with traditional probiotics. Further studies are needed to provide more accurate insight into its mechanisms of action and to better elucidate its properties in several major areas, paving the way for a more integrated and personalized therapeutic approach that finally makes the most of our knowledge of the gut microbiota. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
Prebiotics and Probiotics; https://dx.doi.org/10.3390/nu15081815 |
| DOI: |
10.3390/nu15081815 |
| الاتاحة: |
https://doi.org/10.3390/nu15081815 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: |
edsbas.F9D10083 |
| قاعدة البيانات: |
BASE |