التفاصيل البيبلوغرافية
| العنوان: |
Computerized cognitive remediation training for schizophrenia::An open label, multi-site, multinational methodology study |
| المؤلفون: |
Murthy, N. V., Mahncke, H., Wexler, B. E., Maruff, P., Inamdar, A., Zucchetto, M., Lund, J., Shabbir, S., Shergill, Sukhwinder, Keshavan, M., Kapur, S., Laruelle, M., Alexander, R. |
| المصدر: |
Murthy , N V , Mahncke , H , Wexler , B E , Maruff , P , Inamdar , A , Zucchetto , M , Lund , J , Shabbir , S , Shergill , S , Keshavan , M , Kapur , S , Laruelle , M & Alexander , R 2012 , ' Computerized cognitive remediation training for schizophrenia: An open label, multi-site, multinational methodology study ' , Schizophrenia Research , vol. 139 , no. 1-3 , pp. 87-91 . https://doi.org/10.1016/j.schres.2012.01.042 |
| سنة النشر: |
2012 |
| مصطلحات موضوعية: |
psy, envir |
| الوصف: |
A recent single-site study (Fisher et al., 2009. Am J Psychiatry. 166 (7) 805-11) showed that repeated training with the Brain Fitness Program (BFP) improved performance on a battery of neuropsychological tasks. If replicated these data suggest an important non-pharmacological method for ameliorating cognitive impairment in schizophrenia. Our study evaluated the BFP training effects in an open-label, multi-site, multinational clinical trial. Fifty-five stable adult patients with schizophrenia on regular antipsychotic medication completed >= 32 BFP training sessions over 8-10 weeks. Training effects on cognitive performance and functional capacity outcome measures were measured using CogState (R) schizophrenia battery, UCSD Performance based Skills Assessment (UPSA-2) and Cognitive Assessment Interview (CAI). BFP training showed a large and significant treatment effect on a training exercise task (auditory processing speed), however this effect did not generalize to improved performance on independent CogState (R) assessment. There were no significant effects on UPSA-2 or CAI scores. Our study demonstrated the feasibility of implementing BFP training in a multi-site study. However, BFP training did not show significant treatment effects on cognitive performance or functional capacity outcome measures despite showing large and significant effects on a training exercise. (C) 2012 Elsevier B.V. All rights reserved. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| Relation: |
https://kclpure.kcl.ac.uk/portal/en/publications/computerized-cognitive-remediation-training-for-schizophrenia(703bb44e-99f6-4b76-b9e7-fc6dcc452551).html |
| الاتاحة: |
https://kclpure.kcl.ac.uk/portal/en/publications/computerized-cognitive-remediation-training-for-schizophrenia(703bb44e-99f6-4b76-b9e7-fc6dcc452551).html |
| Rights: |
undefined |
| رقم الانضمام: |
edsbas.F9AC3A3A |
| قاعدة البيانات: |
BASE |