Academic Journal
Are preterm-born survivors at risk of long-term respiratory disease?
| العنوان: | Are preterm-born survivors at risk of long-term respiratory disease? |
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| المؤلفون: | Kaczmarczyk, Katarzyna, Wiszomirska, Ida, Szturmowicz, Magdalena, Magiera, Andrzej, Błażkiewicz, Michalina |
| المصدر: | Therapeutic Advances in Respiratory Disease ; volume 11, issue 7, page 277-287 ; ISSN 1753-4666 1753-4666 |
| بيانات النشر: | SAGE Publications |
| سنة النشر: | 2017 |
| الوصف: | Background: To evaluate the long-term impact of preterm birth on respiratory function in female patients born preterm, we undertook spirometric examinations twice, as they reached the age of puberty, then follow-up examinations of part of the same cohort in adulthood. We sought evidence that preterm birth is correlated with poorer spirometric results into adulthood. Methods: A total of 70 girls (aged 12.2 ± 1.5 years in 1997) who had been born preterm (at 34.7 ± 1.86 weeks, none having experienced bronchopulmonary dysplasia) took part in spriometric examinations in 1997 and again in 1998. Of those, after a gap of 17 years, a group of 12 were successfully recontacted and participated in the 2015 examination as adults (then aged 27.6 ± 2.6 years, born at 34.5 ± 1.92 weeks). We compared spirometric results across the adolescent and adult examinations, and compared the adult results with an adult reference group. Results: The percentage values of FEV 1 (forced expiratory volume in 1 s), FVC (forced vital capacity) and MVV (maximal voluntary ventilation) showed significant improvement between the two examinations in the early adolescent period. In adulthood, FEV 1 %pred (percentage predicted forced expiratory volume in 1 s) showed no statistically significant difference. The mean values of both FVC and FVC%pred (percentage predicted forced vital capacity) for the preterm-born group were lower than for the reference group, but this was not statistically significant. The preterm-born group showed lower values of such parameters as forced expiratory flow at 25–75% of FVC, MEF 25 (maximal expiratory flow at 25% of forced vital capacity) and FEV 1 /FVC as compared with the reference group, but again without statistical significance. Conclusions: (1) A somewhat below-norm level of respiratory parameters among preterm-born girls entering pubescence may attest to continued negative impact on their respiratory system. (2) A significant improvement in their spirometric results 1 year later may indicate that pubescence helps ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1177/1753465817710595 |
| الاتاحة: | https://doi.org/10.1177/1753465817710595 https://journals.sagepub.com/doi/pdf/10.1177/1753465817710595 https://journals.sagepub.com/doi/full-xml/10.1177/1753465817710595 |
| Rights: | https://journals.sagepub.com/page/policies/text-and-data-mining-license |
| رقم الانضمام: | edsbas.F8D92E2F |
| قاعدة البيانات: | BASE |
| DOI: | 10.1177/1753465817710595 |
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