التفاصيل البيبلوغرافية
العنوان: |
Effects of sitagliptin on beta-adrenoceptor mediated relaxation in streptozotocin-diabetic rat aorta |
المؤلفون: |
Muderrisoglu, Ayhanim Elif, Erdogan, Betul Rabia, Yesilyurt, Zeynep Elif, Boztas, Ceren Uyar, Karacomerlioglu, Irem, Altan, Vecdi Melih, Inan, Ebru Arioglu |
المصدر: |
TURKISH JOURNAL OF MEDICAL SCIENCES 51(2) 864-872 |
سنة النشر: |
2021 |
الوصف: |
Background/aim: Dipeptidyl peptidase-4 (DPP4) inhibitors, a class of oral antidiabetic drugs, have been shown to be protective on the vascular system because of their antiinflammatory, antiatherosclerotic, and vasodilatory effects. beta(2)-adrenoceptors (beta(2)-ARs) mediate the vasorelaxation in the aorta. However, beta(3)-adrenoceptor-mediated relaxation has not been studied in diabetic aorta yet. Thus, we aimed to study the effect of sitagliptin treatment on beta(2)- and beta(3)-adrenoceptor-mediated relaxations in the diabetic rat aorta. |
نوع الوثيقة: |
article in journal/newspaper |
اللغة: |
unknown |
Relation: |
https://aperta.ulakbim.gov.tr/record/230430; oai:aperta.ulakbim.gov.tr:230430 |
الاتاحة: |
https://aperta.ulakbim.gov.tr/record/230430 |
Rights: |
info:eu-repo/semantics/openAccess ; http://www.opendefinition.org/licenses/cc-by |
رقم الانضمام: |
edsbas.F8898812 |
قاعدة البيانات: |
BASE |