Academic Journal

Effects of sitagliptin on beta-adrenoceptor mediated relaxation in streptozotocin-diabetic rat aorta

التفاصيل البيبلوغرافية
العنوان: Effects of sitagliptin on beta-adrenoceptor mediated relaxation in streptozotocin-diabetic rat aorta
المؤلفون: Muderrisoglu, Ayhanim Elif, Erdogan, Betul Rabia, Yesilyurt, Zeynep Elif, Boztas, Ceren Uyar, Karacomerlioglu, Irem, Altan, Vecdi Melih, Inan, Ebru Arioglu
المصدر: TURKISH JOURNAL OF MEDICAL SCIENCES 51(2) 864-872
سنة النشر: 2021
الوصف: Background/aim: Dipeptidyl peptidase-4 (DPP4) inhibitors, a class of oral antidiabetic drugs, have been shown to be protective on the vascular system because of their antiinflammatory, antiatherosclerotic, and vasodilatory effects. beta(2)-adrenoceptors (beta(2)-ARs) mediate the vasorelaxation in the aorta. However, beta(3)-adrenoceptor-mediated relaxation has not been studied in diabetic aorta yet. Thus, we aimed to study the effect of sitagliptin treatment on beta(2)- and beta(3)-adrenoceptor-mediated relaxations in the diabetic rat aorta.
نوع الوثيقة: article in journal/newspaper
اللغة: unknown
Relation: https://aperta.ulakbim.gov.tr/record/230430; oai:aperta.ulakbim.gov.tr:230430
الاتاحة: https://aperta.ulakbim.gov.tr/record/230430
Rights: info:eu-repo/semantics/openAccess ; http://www.opendefinition.org/licenses/cc-by
رقم الانضمام: edsbas.F8898812
قاعدة البيانات: BASE