التفاصيل البيبلوغرافية
| العنوان: |
Fibrosarcoma: a challenging diagnosis |
| المؤلفون: |
Ferreira, Cristiane Rúbia, Fonseca, Leonardo Gomes da, Piotto, Gustavo Henrique Munhoz, Geyer, Felipe Correa, Alcântara, Paulo Sérgio Martins de |
| المصدر: |
Autopsy and Case Reports; Vol. 3 Núm. 3 (2013); 21-29 ; Autopsy and Case Reports; v. 3 n. 3 (2013); 21-29 ; Autopsy and Case Reports; Vol. 3 No. 3 (2013); 21-29 ; 2236-1960 |
| بيانات النشر: |
Universidade de São Paulo. Hospital Universitário |
| سنة النشر: |
2013 |
| المجموعة: |
Universidade de São Paulo: Portal de Revistas da USP |
| مصطلحات موضوعية: |
Fibrosarcoma, MUC4 protein, human, Drug Therapy, Surgical Procedures, Operative |
| الوصف: |
Fibrosarcoma represent a rare group of soft tissue malignancies derived from fibrous connective tissue and immature proliferating fibroblasts or undifferentiated anaplastic spindle cells. It affects patients in the fourth and fifth decade of life. Fibrosarcomas can be classified in subtypes such as low-grade fibromyxoid sarcoma (LGFMS) and sclerosing epithelioid fibrosarcoma (SEF),and others. Histological features that overlap between types of fibrosarcomas is well known and reported in the literature. We report the case of a 53-year-old patient who presented a tumor in the axillary fossa, which was initially diagnosed as a solitary fibrous tumor. Due to recurrence of the lesion, as well as the presence of distant metastases, the histological revision considered the diagnosis of breast metaplastic carcinoma, since the tumor expressed the p63 antigen and estrogen and progesterone receptors. Unexpected resistance to chemotherapy motivated the diagnosis re-evaluation, which was due to MUC4 expression and morphological characteristics concluded by a hybrid LGFMSSEF tumor. The authors call attention to the difficult diagnosis in cases of soft tissue tumors. A broad panel of immunohistochemical research is required as the clinical course is essential to the final diagnosis. |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
https://www.revistas.usp.br/autopsy/article/view/75884/79385; https://www.revistas.usp.br/autopsy/article/view/75884 |
| الاتاحة: |
https://www.revistas.usp.br/autopsy/article/view/75884 |
| Rights: |
Copyright (c) 2017 Autopsy and Case Reports |
| رقم الانضمام: |
edsbas.F835B426 |
| قاعدة البيانات: |
BASE |