Academic Journal
Palladium-Catalyzed Regioselective Alkoxylation via C-H Bond Activation in the Dihydrobenzo[c]acridine Series
| العنوان: | Palladium-Catalyzed Regioselective Alkoxylation via C-H Bond Activation in the Dihydrobenzo[c]acridine Series |
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| المؤلفون: | Large, Benjamin, Bourdreux, Flavien, Damond, Aurélie, Gaucher, Anne, Prim, Damien |
| المساهمون: | Institut Lavoisier de Versailles (ILV), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS) |
| المصدر: | ISSN: 2073-4344 ; Catalysts ; https://hal.science/hal-03119329 ; Catalysts, 2018, 8 (4), pp.139. ⟨10.3390/catal8040139⟩. |
| بيانات النشر: | HAL CCSD MDPI |
| سنة النشر: | 2018 |
| المجموعة: | Université de Versailles Saint-Quentin-en-Yvelines: HAL-UVSQ |
| مصطلحات موضوعية: | C-H activation, palladium, alkoxylation, dihydrobenzo[c]acridine, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.CATA]Chemical Sciences/Catalysis |
| الوصف: | International audience ; 5,6-Dihydrobenzo[c]acridine belongs to the large aza-polycyclic compound family. Such molecules are not fully planar due to the presence of a partially hydrogenated ring. This paper describes the first Pd-catalyzed alkoxylation via C-H bond activation of variously substituted 5,6-dihydrobenzo[c]acridines. We determined suitable conditions to promote the selective formation of C-O bonds using 10% Pd(OAc)2, PhI(OAc)2 (2 eq.) and MeOH as the best combination of oxidant and solvent, respectively. Under these conditions, 5,6-dihydrobenzo[c]acridines bearing substituents at both rings A and D were successfully functionalized, giving access to polysubstitutited acridine motifs |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | hal-03119329; https://hal.science/hal-03119329; https://hal.science/hal-03119329/document; https://hal.science/hal-03119329/file/catalysts-08-00139.pdf |
| DOI: | 10.3390/catal8040139 |
| الاتاحة: | https://hal.science/hal-03119329 https://hal.science/hal-03119329/document https://hal.science/hal-03119329/file/catalysts-08-00139.pdf https://doi.org/10.3390/catal8040139 |
| Rights: | http://creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.F813DE57 |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/catal8040139 |
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