Academic Journal
942. Comparison of Antibiotic Susceptibility Across Minnesota Hospitals in 2019 and 2020 Using a New Statewide Antibiogram
| العنوان: | 942. Comparison of Antibiotic Susceptibility Across Minnesota Hospitals in 2019 and 2020 Using a New Statewide Antibiogram |
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| المؤلفون: | Anderson, Jadyn C, Hirsch, Elizabeth B, Rivers, Jennifer, Beaudoin, Amanda, Spaulding, Alicen B |
| المصدر: | Open Forum Infectious Diseases ; volume 9, issue Supplement_2 ; ISSN 2328-8957 |
| بيانات النشر: | Oxford University Press (OUP) |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Infectious Diseases, Oncology |
| الوصف: | Background Surveillance is imperative to successful antibiotic stewardship, but active surveillance is resource-intensive. Regional antibiograms provide a supplementary method of surveillance while conserving resources. We developed the first statewide antibiograms to track susceptibility across the state of Minnesota and compared 2019 and 2020 data. Methods Hospital antibiograms for 2019 and 2020 were submitted to the Minnesota Department of Health in January 2022. Twelve organisms (Enterococcus faecalis, Enterococcus faecium, methicillin-resistant Staphylococcus aureus, methicillin-susceptible S. aureus, S. aureus, Acinetobacter spp., Enterobacter spp., Escherichia coli, Klebsiella aerogenes, K. oxytoca, K. pneumoniae, and Pseudomonas aeruginosa) were selected for analysis against 32 drugs, leading to a total of 142 unique organism/agent combinations. The number of isolates and percent susceptibility from each antibiogram were used to calculate a weighted average percent susceptibility as the state-level susceptibility. Chi-square analysis compared the proportion of susceptible to non-susceptible isolates between the years. Results Submitted antibiograms (n=40) represented 30% of Minnesota hospitals. The total number of isolates reported decreased by 5% from 2019 (n=85,010) to 2020 (n=80,781), with E. coli having the greatest proportion (2019=41.7%, 2020=39.5%) of the total isolates. Significant changes in susceptibility proportions occurred in 33% of analyzed organism/agent combinations, with 68% of these showing increased susceptibility in 2020 compared to 2019. All antibiotics tested against P. aeruginosa demonstrated a statistical increase in susceptibility from 2019 to 2020 (Figure 1). Figure 1 Statewide susceptibility profile of P. aeruginosa in Minnesota, 2019 and 2020. Antimicrobial agents grouped by class from narrow spectrum to broad spectrum, cephalosporins ordered by generation. *denotes statistical significance (p<0.05). Conclusion Analysis of statewide antibiograms for 2019 and ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1093/ofid/ofac492.785 |
| الاتاحة: | http://dx.doi.org/10.1093/ofid/ofac492.785 https://academic.oup.com/ofid/article-pdf/9/Supplement_2/ofac492.785/47891067/ofac492.785.pdf |
| Rights: | https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: | edsbas.F6DD88C6 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/ofid/ofac492.785 |
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