Academic Journal
Benefits and harms of antenatal and newborn screening programmes in health economic assessments: the VALENTIA systematic review and qualitative investigation.
| العنوان: | Benefits and harms of antenatal and newborn screening programmes in health economic assessments: the VALENTIA systematic review and qualitative investigation. |
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| المؤلفون: | Rivero-Arias, O, Png, ME, White, A, Yang, M, Taylor-Phillips, S, Hinton, L, Boardman, F, McNiven, A, Fisher, J, Thilaganathan, B, Oddie, S, Slowther, A-M, Ratushnyak, S, Roberts, N, Shilton Osborne, J, Petrou, S |
| بيانات النشر: | NIHR Journals Library |
| سنة النشر: | 2024 |
| المجموعة: | St George's University of London: Repository |
| الوصف: | BACKGROUND: Health economic assessments are used to determine whether the resources needed to generate net benefit from an antenatal or newborn screening programme, driven by multiple benefits and harms, are justifiable. It is not known what benefits and harms have been adopted by economic evaluations assessing these programmes and whether they omit benefits and harms considered important to relevant stakeholders. OBJECTIVES: (1) To identify the benefits and harms adopted by health economic assessments in this area, and to assess how they have been measured and valued; (2) to identify attributes or relevance to stakeholders that ought to be considered in future economic assessments; and (3) to make recommendations about the benefits and harms that should be considered by these studies. DESIGN: Mixed methods combining systematic review and qualitative work. SYSTEMATIC REVIEW METHODS: We searched the published and grey literature from January 2000 to January 2021 using all major electronic databases. Economic evaluations of an antenatal or newborn screening programme in one or more Organisation for Economic Co-operation and Development countries were considered eligible. Reporting quality was assessed using the Consolidated Health Economic Evaluation Reporting Standards checklist. We identified benefits and harms using an integrative descriptive analysis and constructed a thematic framework. QUALITATIVE METHODS: We conducted a meta-ethnography of the existing literature on newborn screening experiences, a secondary analysis of existing individual interviews related to antenatal or newborn screening or living with screened-for conditions, and a thematic analysis of primary data collected with stakeholders about their experiences with screening. RESULTS: The literature searches identified 52,244 articles and reports, and 336 unique studies were included. Thematic framework resulted in seven themes: (1) diagnosis of screened for condition, (2) life-years and health status adjustments, (3) treatment, (4) long-term ... |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://openaccess.sgul.ac.uk/id/eprint/116651/1/3045441.pdf; Rivero-Arias, O; Png, ME; White, A; Yang, M; Taylor-Phillips, S; Hinton, L; Boardman, F; McNiven, A; Fisher, J; Thilaganathan, B; et al. Rivero-Arias, O; Png, ME; White, A; Yang, M; Taylor-Phillips, S; Hinton, L; Boardman, F; McNiven, A; Fisher, J; Thilaganathan, B; Oddie, S; Slowther, A-M; Ratushnyak, S; Roberts, N; Shilton Osborne, J; Petrou, S (2024) Benefits and harms of antenatal and newborn screening programmes in health economic assessments: the VALENTIA systematic review and qualitative investigation. Health Technol Assess, 28 (25). pp. 1-180. ISSN 2046-4924 https://doi.org/10.3310/PYTK6591 SGUL Authors: Thilaganathan, Baskaran |
| DOI: | 10.3310/PYTK6591 |
| الاتاحة: | https://openaccess.sgul.ac.uk/id/eprint/116651/ https://openaccess.sgul.ac.uk/id/eprint/116651/1/3045441.pdf https://doi.org/10.3310/PYTK6591 |
| Rights: | cc_by_4 |
| رقم الانضمام: | edsbas.F6B2CEDE |
| قاعدة البيانات: | BASE |
| DOI: | 10.3310/PYTK6591 |
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