Academic Journal
LIMITS AND POSSIBILITIES IN A PRIMARY SELECTIVE IgA DEFICIENCY TREATMENT – CASE PRESENTATION
| العنوان: | LIMITS AND POSSIBILITIES IN A PRIMARY SELECTIVE IgA DEFICIENCY TREATMENT – CASE PRESENTATION |
|---|---|
| المؤلفون: | Monica Alexoae, Mihaela Bataneant, Ileana Ioniuc, Alina Murgu, Alice Azoicai, Aurica Rugina |
| المصدر: | Romanian Journal of Pediatrics, Vol 66, Iss 2, Pp 123-126 (2017) |
| بيانات النشر: | Amaltea Medical Publishing House |
| سنة النشر: | 2017 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | primary selective iga deficiency, igg4 subclass, Medicine, Pediatrics, RJ1-570 |
| الوصف: | The primary deficit of IgA is the most common congenital immunodeficiency defined by the values of serum IgA below 0.07 g/l and normal values of IgG and IgM. Most cases are asymptomatic, only 10-15% is manifested by recurrent or persistent sinopulmonary infections, autoimmune diseases, allergies, malignancies. Some cases develop over the time a common variable immunodeficiency. The frequency of anti-IgA antibody justifies the cautiously use of transfusions of blood, plasma or intravenous immunoglobulin. The authors present a case of primary selective IgA deficiency, where the severity of infectious exacerbations appears to be due to the combination of a lack of IgG4, and discuss the possibilities and limits of therapy in light of recent data from the literature. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1454-0398 2069-6175 |
| Relation: | https://revistemedicale.amaltea.ro/Romanian_Journal_of_PEDIATRICS/Revista_Romana_de_PEDIATRIE-2017-Nr.2/RJP_2017_2_EN_Art-07.pdf; https://doaj.org/toc/1454-0398; https://doaj.org/toc/2069-6175; https://doaj.org/article/8bdc61876ade4ccf89136fc87b229fd0 |
| DOI: | 10.37897/RJP.2017.2.7 |
| الاتاحة: | https://doi.org/10.37897/RJP.2017.2.7 https://doaj.org/article/8bdc61876ade4ccf89136fc87b229fd0 |
| رقم الانضمام: | edsbas.F6A813E3 |
| قاعدة البيانات: | BASE |
| تدمد: | 14540398 20696175 |
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| DOI: | 10.37897/RJP.2017.2.7 |