Academic Journal
Survival and neurological outcome after bystander versus lay responder defibrillation in out-of-hospital cardiac arrest:A sub-study of the BOX trial
العنوان: | Survival and neurological outcome after bystander versus lay responder defibrillation in out-of-hospital cardiac arrest:A sub-study of the BOX trial |
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المؤلفون: | Sarkisian, Laura, Isse, Yusuf Abdi, Gerke, Oke, Obling, Laust Emil Roelsgaard, Paulin Beske, Ramus, Grand, Johannes, Schmidt, Henrik, Højgaard, Henrik Frederiksen, Meyer, Martin Abild Stengaard, Borregaard, Britt, Hassager, Christian, Kjaergaard, Jesper, Møller, Jacob Eifer |
المصدر: | Sarkisian , L , Isse , Y A , Gerke , O , Obling , L E R , Paulin Beske , R , Grand , J , Schmidt , H , Højgaard , H F , Meyer , M A S , Borregaard , B , Hassager , C , Kjaergaard , J & Møller , J E 2024 , ' Survival and neurological outcome after bystander versus lay responder defibrillation in out-of-hospital cardiac arrest : A sub-study of the BOX trial ' , Resuscitation , vol. 195 , 110059 . https://doi.org/10.1016/j.resuscitation.2023.110059 |
سنة النشر: | 2024 |
المجموعة: | University of Southern Denmark: Research Output / Syddansk Universitet |
مصطلحات موضوعية: | Bystander, Cardiac arrest, Defibrillation, Lay responder, OHCA, Resuscitation, Brain Death, Out-of-Hospital Cardiac Arrest, Humans, Electric Countershock, Clinical Trials as Topic, Cardiopulmonary Resuscitation, Registries, Emergency Medical Services |
الوصف: | Background and aim: Bystander defibrillation is associated with increased survival with good neurological outcome after out-of-hospital cardiac arrest (OHCA). Dispatch of lay responders could increase defibrillation rates, however, survival with good neurological outcome in these remain unknown. The aim was to compare long-term survival with good neurological outcome in bystander versus lay responder defibrillated OHCAs. Methods: This is a sub-study of the BOX trial, which included OHCA patients from two Danish tertiary cardiac intensive care units from March 2017 to December 2021. The main outcome was defined as 3-month survival with good neurological performance (Cerebral Performance Category of 1or 2, on a scale from 1 (good cerebral performance) to 5 (death or brain death)). For this study EMS witnessed OHCAs were excluded. Results: Of the 715 patients, a lay responder arrived before EMS in 125 cases (16%). In total, 81 patients were defibrillated by a lay responder (11%), 69 patients by a bystander (10%) and 565 patients by the EMS staff (79%). The 3-month survival with good neurological outcome was 65% and 81% in the lay responder and bystander defibrillated groups, respectively (P = 0.03). Conclusion: In patients with OHCA, 3-month survival with good neurological outcome was higher in bystander defibrillated patients compared with lay responder defibrillated patients. |
نوع الوثيقة: | article in journal/newspaper |
وصف الملف: | application/pdf |
اللغة: | English |
DOI: | 10.1016/j.resuscitation.2023.110059 |
الاتاحة: | https://portal.findresearcher.sdu.dk/da/publications/60a1312e-59ec-445a-a5ed-38162049b653 https://doi.org/10.1016/j.resuscitation.2023.110059 https://findresearcher.sdu.dk/ws/files/255906554/PIIS0300957223007955.pdf |
Rights: | info:eu-repo/semantics/openAccess |
رقم الانضمام: | edsbas.F64F44B8 |
قاعدة البيانات: | BASE |
DOI: | 10.1016/j.resuscitation.2023.110059 |
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