Academic Journal
Staged management of infection with adjustable spacers after megaprosthesis implantation in primary sarcoma patients
| العنوان: | Staged management of infection with adjustable spacers after megaprosthesis implantation in primary sarcoma patients |
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| المؤلفون: | ŞİRİN, EVRİM, AKGÜLLE, AHMET HAMDİ, EROL, BÜLENT |
| المساهمون: | ŞİRİN E., Sofulu O., Baysal O., AKGÜLLE A. H., EROL B. |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Tıp, Cerrahi Tıp Bilimleri, Ortopedi ve Travmatoloji, Sağlık Bilimleri, Medicine, Surgery Medicine Sciences, Orthopedics and Traumatology, Health Sciences, ORTOPEDİ, Klinik Tıp, Klinik Tıp (MED), ORTHOPEDICS, CLINICAL MEDICINE, Clinical Medicine (MED), Ayak Bakımı, Ortopedi ve Spor Hekimliği, Podiatry, Orthopedics and Sports Medicine, Musculoskeletal sarcoma, Mega-prosthesis, Infection, Staged revision, Spacer, BONE-TUMOR RESECTION, ENDOPROSTHETIC RECONSTRUCTION, DEEP INFECTION, DISTAL TIBIA, KNEE, OSTEOSARCOMA, PROSTHESES |
| الوصف: | BackgroundWhile periprosthetic joint infection has always been a significant concern for orthopaedic surgeons, the rate of infection is five to ten times higher after tumor prosthesis implantation. With the growing use of mega-implants, the number of these infections has also increased. We aimed to investigate the results of our patients with a primary malignant musculoskeletal tumor, who underwent two-stage revision surgery for an infected mega-prosthesis. We also presented the emerging complicatons and required soft tissue reconstruction procedures.MethodsThe study included 32 primary bone and soft tissue sarcoma patients who underwent a two-stage revision procedure for infection. After a rigorous bone and soft tissue debridement procedure at the first stage, antibiotic-loaded bone cement was wrapped around a cloverleaf type intramedullary nail and inserted into the forming gap. After a minimum of 6 weeks of antibiotic therapy, depending on patients\" clinical signs and serum infection markers, the reimplantation stage was undertaken.ResultsThe mean oncologic follow-up period was 28 months (range 5-96 months). During this period, 11 patients died because of non-infection related causes, 12 patients were alive with their disease, whereas 9 patients were totally free of their oncologic condition. The infection was eradicated in all survivors except one patient, where a high-level transfemoral amputation became necessary.ConclusionPeriprosthetic infection after tumor proshesis implantation in cancer patients can be managed with same principles as conventional arthroplaty procedures, taking care that they are immunocompromised and vulnerable patients and their bone stock loss is significant which makes surgical options more challenging. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0019-5413 |
| Relation: | INDIAN JOURNAL OF ORTHOPAEDICS; ŞİRİN E., Sofulu O., Baysal O., AKGÜLLE A. H., EROL B., "Staged Management of Infection with Adjustable Spacers After Megaprosthesis Implantation in Primary Sarcoma Patients", INDIAN JOURNAL OF ORTHOPAEDICS, 2023; https://hdl.handle.net/11424/288719 |
| DOI: | 10.1007/s43465-023-00876-9 |
| الاتاحة: | https://hdl.handle.net/11424/288719 https://doi.org/10.1007/s43465-023-00876-9 |
| Rights: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.F329B3AB |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 00195413 |
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| DOI: | 10.1007/s43465-023-00876-9 |