Academic Journal
A Rare Case of Primary Cutaneous Gamma-Delta T-cell Lymphoma with Aberrant B-cell Marker Expression
| العنوان: | A Rare Case of Primary Cutaneous Gamma-Delta T-cell Lymphoma with Aberrant B-cell Marker Expression |
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| المؤلفون: | Trivedi, Apoorva, Yabe, Mariko, Dogan, Ahmet, Epstein-Peterson, Zachary D., Myskowski, Patricia L., Arcila, Maria E., Linos, Konstantinos |
| المصدر: | The American Journal of Dermatopathology ; volume 45, issue 11, page 768-772 ; ISSN 0193-1091 |
| بيانات النشر: | Ovid Technologies (Wolters Kluwer Health) |
| سنة النشر: | 2023 |
| الوصف: | Primary cutaneous gamma-delta T-cell lymphoma (PCGDTL) is a rare and diagnostically challenging primary skin lymphoma. We present a case of a 78-year-old otherwise healthy man who developed nonhealing nodules on his right posterior calf. Initial biopsy showed a dense, atypical, lymphoid infiltrate with gamma-delta and cytotoxic T-cell immunophenotypes. The diagnosis of PCGDTL was rendered; however, concurrent flow cytometry revealed expression of aberrant B-cell markers, including CD19 and cytoplasmic CD79a. Subsequent immunohistochemical studies corroborated this result. We report the extremely rare phenomenon of aberrant B-cell marker expression in PCGDTL, the first formally reported case to our knowledge. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1097/dad.0000000000002557 |
| DOI: | 10.1097/DAD.0000000000002557 |
| الاتاحة: | http://dx.doi.org/10.1097/dad.0000000000002557 https://journals.lww.com/10.1097/DAD.0000000000002557 |
| رقم الانضمام: | edsbas.F22FA537 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1097/dad.0000000000002557 |
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