التفاصيل البيبلوغرافية
| العنوان: |
Association analysis with breast cancer related outcomes. |
| المؤلفون: |
Diptavo Dutta (12111132), Ananda Sen (39245), Jaya Satagopan (70346) |
| سنة النشر: |
2022 |
| مصطلحات موضوعية: |
Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, sparse canonical correlation, key biological pathways, gain comprehensive insights, dna repair pathways, aggregate weaker associations, regulating molecular phenotypes, identified several genes, interpretable regulatory associations, censored disease endpoints, cancer genome atlas, genes significantly associated, identify key groups, associated gene modules, identify interpretable, regulatory modules, molecular biomarkers, important genes, genes within, gene modules, gene expressions |
| الوصف: |
(A) DNALI1 gene on chromosome 1 associated with ER status and trans-regulated by a CNA of transcription factor CHD1 on chromosome 5. (B) Trans regulation of CD2BP2 gene on chromosome 16p11.2 by a CNA in ZNF263 gene located in chromosome 16q13.3 which are approximately 27Mb apart. (C) Association of CD2BP2 expression level with overall survival probability. Expression levels have been dichotomized as high and low using 75-th percentile as cut-off. (D) p-values of 72 genes identified to be strongly associated (p-value < 2.5 х 10 −06 ) with multiple outcomes, across the 7 outcomes. P-values < 1 х 10 −12 are collapsed to 1 х 10 −12 for the ease of viewing. |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/Association_analysis_with_breast_cancer_related_outcomes_/21796336 |
| DOI: |
10.1371/journal.pone.0276886.g003 |
| الاتاحة: |
https://doi.org/10.1371/journal.pone.0276886.g003 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.F2056C0B |
| قاعدة البيانات: |
BASE |