Academic Journal
A Prevalent Y;15 Translocation in the Ethiopian Beta Israel Community in Israel
| العنوان: | A Prevalent Y;15 Translocation in the Ethiopian Beta Israel Community in Israel |
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| المؤلفون: | Chen-Shtoyerman, R., Josefsberg Ben-Yehoshua, S., Nissani, R., Rosensaft, J., Appelman, Z. |
| المصدر: | Cytogenetic and Genome Research ; volume 136, issue 3, page 171-174 ; ISSN 1424-8581 1424-859X |
| بيانات النشر: | S. Karger AG |
| سنة النشر: | 2012 |
| الوصف: | We describe 7 cases of abnormal karyotypes involving chromosomes Y and 15 in Ethiopian Beta Israel patients: 46,XX, der(15)t(Y;15)(q12;p12) and 46,XY,der(15)t(Y;15)(q12;p12). Six cases were incidentally found in amniocentesis performed for various indications; the indication for karyotyping in 1 case was recurrent abortions. To the best of our knowledge, this is the first report of this translocation in a specific ethnic group. We conclude that the derivative chromosome 15 with chromosome Y is probably a normal variant in Ethiopian Beta Israel occurring at an estimated frequency of 4/74 (5.4%). The prenatal diagnosis of this translocation in this population probably does not require further parental testing. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1159/000336201 |
| الاتاحة: | http://dx.doi.org/10.1159/000336201 https://www.karger.com/Article/Pdf/336201 |
| Rights: | https://www.karger.com/Services/SiteLicenses ; https://www.karger.com/Services/SiteLicenses |
| رقم الانضمام: | edsbas.F1D3CA37 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1159/000336201 |
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