Academic Journal
Bisphosphonate chelating agents: complexation of Fe(III) and Al(III) by 1-phenyl-1-hydroxymethylene bisphosphonate and its analogues
| العنوان: | Bisphosphonate chelating agents: complexation of Fe(III) and Al(III) by 1-phenyl-1-hydroxymethylene bisphosphonate and its analogues |
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| المؤلفون: | GUMIENNA KONTECKA E., SILVAGNI R., LIPINSKI R., LECOUVEY M., LEROUX Y., KOZLOWSKI H., CESARE MARINCOLA, FLAMINIA, CRISPONI, GUIDO, NURCHI, VALERIA MARINA |
| المساهمون: | GUMIENNA KONTECKA, E., Silvagni, R., Lipinski, R., Lecouvey, M., CESARE MARINCOLA, Flaminia, Crisponi, Guido, Nurchi, VALERIA MARINA, Leroux, Y., Kozlowski, H. |
| سنة النشر: | 2002 |
| المجموعة: | Università degli Studi di Cagliari: UNICA IRIS |
| الوصف: | Bisphosphonate ligands were found to be very efficient chelating agents for both Al(III) and Fe(III) ions. Potentiometric and spectroscopic data allow evaluation of the coordination equilibria in the solutions containing 1-phenyl-1-hydroxymethylene bisphosphonate and its three analogues with Al(III) and Fe(III) ions. At pH below 4 the bis-complexes are formed, while above pH 4 the major species are equimolar, monomeric for Al(III) or dimeric for Fe(III) complexes. The large steric hindrance and high electric charge are the major factors influencing the complex stoichiometry. The formation of the dimeric Fe(III) with mu-oxo or mu-hydroxo bridges were supported by measurements of the magnetic moments using Evans' method. The stabilities of the complexes formed are higher than those found for deferiprone, L1, used in clinics as a chelating agent. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| Relation: | info:eu-repo/semantics/altIdentifier/wos/WOS:000179281100015; volume:339; firstpage:111; lastpage:118; numberofpages:8; journal:INORGANICA CHIMICA ACTA; http://hdl.handle.net/11584/94285; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-0037112054 |
| DOI: | 10.1016/S0020-1693(02)00918-0 |
| الاتاحة: | http://hdl.handle.net/11584/94285 https://doi.org/10.1016/S0020-1693(02)00918-0 |
| رقم الانضمام: | edsbas.F1A71C6D |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/S0020-1693(02)00918-0 |
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