Academic Journal
Iron Parameters as a Graft Function Indicator in Renal Transplant Recipients ; Böbrek Nakli Olan Hastalarda Greft Fonksiyon Göstergesi Olarak Demir Parametreleri
العنوان: | Iron Parameters as a Graft Function Indicator in Renal Transplant Recipients ; Böbrek Nakli Olan Hastalarda Greft Fonksiyon Göstergesi Olarak Demir Parametreleri |
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المؤلفون: | Özgür, Yasemin, Gücün, Murat, Tanrıkulu, Seher, Demirbaş, Zeynep Ece, Erkılınç, Gamze, Titiz, Mesut İzzet, Şahin, Gülizar |
سنة النشر: | 2019 |
الوصف: | Objective: For those with severe kidney disease, renal transplantation is the best treatmentoption when compared with dialysis methods; however, it is important to consider potentialcomplications that may occur and the negative effects on graft survival. The aim of this studywas to investigate the effects of iron parameters on the development of post-transplantanemia (PTA) and post-transplant erythrocytosis (PTE).Methods: This retrospective study was conducted with 214 renal transplant recipients.PTA was defined as a hemoglobin (Hb) level of <13g/dL for men and <12g/dL for women 6months after transplantation, PTE was defined as an Hb level of >17g/dL for men and >15g/dL for women. The remaining patients were defined as the control group.Results: PTA developed in 79 patients (36.9%), and PTE developed in 25 patients (11.7%).The iron level was lower in the PTE group before the transplantation and in the first 3months after transplantation; however, it was also determined that in the PTA group, theiron level was low at 6 and 12 months. Even though the PTA patients’ transferrin saturation(TS) was rose significantly in the first month after transplant, it was observed that the TSwas lower in the PTE group at all time points.Conclusion: Even if iron levels are low before kidney transplantation in case of properreplecement is performed and graft functions are intact; anemia may improve and even polycythemia may develop. TS increased in the initial post-transplant period; it may be an earlyindicator of PTA and the development of graft function failure. ; Amaç: Böbrek nakli, diyaliz yöntemlerine kıyasla en iyi tedavi seçeneği olmakla birlikte sonrasında meydana gelen komplikasyonlar greft sağ kalımına olumsuz etkileri nedeniyle önemlidir. Bu çalışmanın amacı, demir parametrelerinin post transplant anemi (PTA) ve post transplant eritrositoz (PTE) gelişimi üzerine etkilerini araştırmaktır. Gereç ve Yöntem: Bu retrospektif çalışmamıza böbrek nakli yapılmış 214 hasta dahil edildi. Nakil sonrası altıncı aydan ... |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 2587-0998 2587-1404 |
Relation: | Southern Clinics of Istanbul Eurasia; https://doi.org/10.14744/scie.2018.26928; https://app.trdizin.gov.tr/makale/TXpRMU5EQTRPQT09; https://hdl.handle.net/20.500.11776/8113; 30; 14; 19; TXpRMU5EQTRPQT09 |
DOI: | 10.14744/scie.2018.26928 |
الاتاحة: | https://hdl.handle.net/20.500.11776/8113 https://doi.org/10.14744/scie.2018.26928 https://app.trdizin.gov.tr/makale/TXpRMU5EQTRPQT09 |
Rights: | info:eu-repo/semantics/openAccess |
رقم الانضمام: | edsbas.F120CE1F |
قاعدة البيانات: | BASE |
تدمد: | 25870998 25871404 |
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DOI: | 10.14744/scie.2018.26928 |