Academic Journal
Conformation of poly(γ‐glutamic acid) in aqueous solution
| العنوان: | Conformation of poly(γ‐glutamic acid) in aqueous solution |
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| المؤلفون: | Muroga, Yoshio, Nakaya, Asami, Inoue, Atsuki, Itoh, Daiki, Abiru, Masaya, Wada, Kaori, Takada, Masako, Ikake, Hiroki, Shimizu, Shigeru |
| المصدر: | Biopolymers ; volume 105, issue 4, page 191-198 ; ISSN 0006-3525 1097-0282 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2016 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Local conformation and overall conformation of poly(γ‐DL‐glutamic acid) (PγDLGA) and poly(γ‐L‐glutamic acid) (PγLGA) in aqueous solution was studied as a function of degree of ionization ε by 1 H‐NMR, circular dichroism, and potentiometric titration. It was clarified that their local conformation is represented by random coil over an entire ε range and their overall conformation is represented by expanded random‐coil in a range of ε > ε * , where ε * is about 0.3, 0.35, 0.45, and 0.5 for added‐salt concentration of 0.02M, 0.05M, 0.1M, and 0.2M, respectively. In a range of ε < ε * , however, ε dependence of their overall conformation is significantly differentiated from each other. PγDLGA tends to aggregate intramolecularly and/or intermolecularly with decreasing ε, but PγLGA still behaves as expanded random‐coil. It is speculated that spatial arrangement of adjacent carboxyl groups along the backbone chain essentially affects the overall conformation of PγGA in acidic media. © 2015 Wiley Periodicals, Inc. Biopolymers 105: 191–198, 2016. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/bip.22776 |
| الاتاحة: | http://dx.doi.org/10.1002/bip.22776 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fbip.22776 https://onlinelibrary.wiley.com/doi/pdf/10.1002/bip.22776 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.F0E2162E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/bip.22776 |
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