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Short- and long-term mortality and causes of death in HIV/tuberculosis patients in Europe

التفاصيل البيبلوغرافية
العنوان: Short- and long-term mortality and causes of death in HIV/tuberculosis patients in Europe
المؤلفون: Podlekareva D. N., Panteleev A. M., Grint D., Post F. A., Miro J. M., Bruyand M., Furrer H., Obel N., Girardi E., Vasilenko A., Losso M. H., Arenas-Pinto A., Cayla J., Rakhmanova A., Zeltina I., Werlinrud A. M., Lundgren J. D., Mocroft A., Kirk O., Toibaro J. J., Warley E., Tamayo N., Cristina Ortiz M., Scapelatto P., Bottaro E., Murano F., Miachans M., Contarelli J., Massera L., Corral J., Hualde M., Miglioranza C., Corti M., Metta H., Casiro A., Cuini R., Laplume H., David D., Marson C., Lupo S., Trape L., Garcia Messina O., Gear O., Bruguera J. M., Karpov I., Skrahina E., Skrahin A., Mitsura V., Kozorez E., Ruzanov D., Bondarenko V., Suetnov O., Paduto D., Dabis F., Matteelli A., Carvalho A. C., Basche R., Hamad I. E., Ricci B. A., Maggiolo F., Ravasio V., Mussini C., Prati F., Castelletti S., Spallanzani L., Antinori A., Antonucci G., Bibbolino C., Bove G., Busi Rizzi E., Cicalini S., Conte A., Cuzzi G., De Mori P., Festa A., Goletti D., Grisetti S., Gualano G., Lauria F. N., Maddaluno R., Migliorisi Ramazzini P., Narciso P., Parracino L., Palmieri F., Petrosillo N., Pucillo L., Puro V., Vanacore P., Urso R., d'Arminio Monforte A., Riekstina V., Aldins P., Duiculescu D., Malashenkov E., Kozlov A., Buzunova S., Manzardo C., Garcia-Goez J. F., Moreno-Camacho A., Martinez J. A., Gonzalez J., Garcia-Alcaide F., Perez I., Gatell J. M., Sanchez P., Lopez-Colomes J. L., Martinez-Lacasa X., Falco V., Imaz A., Ocana I., Vidal R., Sambeat M. A., Moreno-Martinez A., Millet J. P., Fina L., del Bano L., Orcau A., Barth J., Battegay M., Bernasconi E., Boni J., Bucher H. C., Burton-Jeangros C., Calmy A., Cavassini M., Cellerai C., Egger M., Elzi L., Fehr J., Fellay J., Flepp M., Fux C. A., Gorgievski M., Gunthard H., Haerry D., Hasse B., Hirsch H. H., Hirschel B., Hosli I., Kahlert C., Kaiser L., Keiser O., Kind C., Klimkait T., Kovari H., Ledergerber B., Martinetti G., Martinez de Tejada B., Metzner K., Muller N., Nadal D., Pantaleo G., Rauch A., Regenass S., Rickenbach M., Rudin C., Schmid P., Schultze D., Schoni-Affolter F., Schupbach J., Speck R., Taffe P., Tarr P., Telenti A., Trkola A., Vernazza P., Weber R., Yerly S., Campbell L., Miller R., Chentsova N., Podlekareva D., Kjaer J., Duiculesku D.
المساهمون: Podlekareva D. N., Panteleev A. M., Grint D., Post F. A., Miro J. M., Bruyand M., Furrer H., Obel N., Girardi E., Vasilenko A., Losso M. H., Arenas-Pinto A., Cayla J., Rakhmanova A., Zeltina I., Werlinrud A. M., Lundgren J. D., Mocroft A., Kirk O., Toibaro J. J., Warley E., Tamayo N., Cristina Ortiz M., Scapelatto P., Bottaro E., Murano F., Miachans M., Contarelli J., Massera L., Corral J., Hualde M., Miglioranza C., Corti M., Metta H., Casiro A., Cuini R., Laplume H., David D., Marson C., Lupo S., Trape L., Garcia Messina O., Gear O., Bruguera J. M., Karpov I., Skrahina E., Skrahin A., Mitsura V., Kozorez E., Ruzanov D., Bondarenko V., Suetnov O., Paduto D., Dabis F., Matteelli A., Carvalho A. C., Basche R., Hamad I. E., Ricci B. A., Maggiolo F., Ravasio V., Mussini C., Prati F., Castelletti S., Spallanzani L., Antinori A., Antonucci G., Bibbolino C., Bove G., Busi Rizzi E., Cicalini S., Conte A., Cuzzi G., De Mori P., Festa A., Goletti D., Grisetti S., Gualano G., Lauria F. N., Maddaluno R., Migliorisi Ramazzini P., Narciso P., Parracino L., Palmieri F., Petrosillo N., Pucillo L., Puro V., Vanacore P., Urso R., d'Arminio Monforte A., Riekstina V., Aldins P., Duiculescu D., Malashenkov E., Kozlov A., Buzunova S., Manzardo C., Garcia-Goez J. F., Moreno-Camacho A., Martinez J. A.
سنة النشر: 2014
المجموعة: Università degli Studi di Brescia: OPENBS - Open Archive UniBS
مصطلحات موضوعية: Adult, Anti-HIV Agent, Antitubercular Agent, Argentina, Cause of Death, Cohort Studie, Coinfection, Europe, Female, HIV Infection, Human, Male, Multivariate Analysi, Tuberculosis
الوصف: Mortality of HIV/tuberculosis (TB) patients in Eastern Europe is high. Little is known about their causes of death.This study aimed to assess and compare mortality rates and cause of death in HIV/TB patients across Eastern Europe and Western Europe and Argentina (WEA) in an international cohort study. Mortality rates and causes of death were analysed by time from TB diagnosis (<3 months, 3-12 months or >12 months) in 1078 consecutive HIV/TB patients. Factors associated with TB-related death were examined in multivariate Poisson regression analysis.347 patients died during 2625 person-years of follow-up. Mortality in Eastern Europe was three- to ninefold higher than in WEA. TB was the main cause of death in Eastern Europe in 80%, 66% and 61% of patients who died <3 months, 3-12 months or >12 months after TB diagnosis, compared to 50%, 0% and 15% in the same time periods in WEA (p<0.0001). In multivariate analysis, follow-up in WEA (incidence rate ratio (IRR) 0.12, 95% CI 0.04-0.35), standard TB-treatment (IRR 0.45, 95% CI 0.20-0.99) and antiretroviral therapy (IRR 0.32, 95% CI 0.14-0.77) were associated with reduced risk of TB-related death.Persistently higher mortality rates were observed in HIV/TB patients in Eastern Europe, and TB was the dominant cause of death at any time during follow-up. This has important implications for HIV/TB programmes aiming to optimise the management of HIV/TB patients and limit TB-associated mortality in this region.
نوع الوثيقة: article in journal/newspaper
اللغة: English
Relation: info:eu-repo/semantics/altIdentifier/pmid/23766333; info:eu-repo/semantics/altIdentifier/wos/WOS:000329552200022; volume:43; issue:1; firstpage:166; lastpage:177; numberofpages:12; journal:EUROPEAN RESPIRATORY JOURNAL; http://hdl.handle.net/11379/533156; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84891939060
DOI: 10.1183/09031936.00138712
الاتاحة: http://hdl.handle.net/11379/533156
https://doi.org/10.1183/09031936.00138712
رقم الانضمام: edsbas.F0CE7FEB
قاعدة البيانات: BASE
الوصف
DOI:10.1183/09031936.00138712