Antisaccade Deficits in Stiff Person Syndrome

التفاصيل البيبلوغرافية
العنوان: Antisaccade Deficits in Stiff Person Syndrome
المؤلفون: Amrita K. Singh
المساهمون: Amrita Singh, Wangzikang Zhang, Jeffrey Odel, Michael Goldberg, Linus Sun
المصدر: 2017 North American Neuro-Ophthalmology Society Annual Meeting
بيانات النشر: Spencer S. Eccles Health Sciences Library, University of Utah
سنة النشر: 2017
المجموعة: The University of Utah: J. Willard Marriott Digital Library
مصطلحات موضوعية: Paraneoplastic syndromes, Higher Visual Cortical functions, Ocular Motility, Neuro-ophth & systyemic disease, Nystagmus
الوصف: The antisaccade task is a clinically useful sign of frontal cortical dysfunction (Hallet,1978). In this task, subjects must make a saccade away from a salient stimulus to a spatial location reflected 180° away. Normal subjects make about 10% errors in this task, but frontal patients make many more. Stiff Person Syndrome (SPS) is a disorder characterized by muscle rigidity, spasm, and ataxia, in which 85% of patients have antibodies against glutamic acid decarboxylase (GAD) an enzyme necessary for GABA synthesis. Previous studies of these patients have identified oculomotor abnormalities, including esotropia (Economides, 2005), multi-component and slow vertical saccades, decreased smooth pursuit gain, downbeat nystagmus (Ances, 2005), and ophthalmoplegia (Pittock, 2006).
نوع الوثيقة: other/unknown material
وصف الملف: application/pdf
اللغة: unknown
Relation: NANOS 2017: Poster Presentations; Neuro-ophthalmology Virtual Education Library: NOVEL http://NOVEL.utah.edu; 20170402_nanos_posters_102; https://collections.lib.utah.edu/ark:/87278/s6n62fgw
الاتاحة: https://collections.lib.utah.edu/ark:/87278/s6n62fgw
رقم الانضمام: edsbas.EF846CB
قاعدة البيانات: BASE