Academic Journal
RNA Sequencing-Based Transcriptional Overview of Xerotolerance in Cronobacter sakazakii SP291
العنوان: | RNA Sequencing-Based Transcriptional Overview of Xerotolerance in Cronobacter sakazakii SP291 |
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المؤلفون: | Srikumar, Shabarinath, Cao, Yu, Yan, Qiongqiong, Van Hoorde, Koenraad, Nguyen, Scott, Cooney, Shane, Gopinath, Gopal R., Tall, Ben D., Sivasankaran, Sathesh K., Lehner, Angelika, Stephan, Roger, Fanning, Séamus |
المساهمون: | Dudley, Edward G., Department of Agriculture, Food and the Marine, Enterprise Ireland |
المصدر: | Applied and Environmental Microbiology ; volume 85, issue 3 ; ISSN 0099-2240 1098-5336 |
بيانات النشر: | American Society for Microbiology |
سنة النشر: | 2019 |
الوصف: | Cronobacter sakazakii is a pathogen of importance to neonatal health and is known to persist in dry food matrices, such as powdered infant formula (PIF) and its associated production environment. When infections are reported in neonates, mortality rates can be high. The success of this bacterium in surviving these low-moisture environments suggests that Cronobacter species can respond to a variety of environmental signals. Therefore, understanding those signals that aid the persistence of this pathogen in these ecological niches is an important step toward the development of strategies to reduce the risk of contamination of PIF. This research led to the identification of candidate genes that play a role in the persistence of this pathogen in desiccated conditions and, thereby, serve as a model target to design future strategies to mitigate PIF-associated survival of C. sakazakii . |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
DOI: | 10.1128/aem.01993-18 |
DOI: | 10.1128/AEM.01993-18 |
الاتاحة: | http://dx.doi.org/10.1128/aem.01993-18 https://journals.asm.org/doi/pdf/10.1128/AEM.01993-18 |
Rights: | https://journals.asm.org/non-commercial-tdm-license |
رقم الانضمام: | edsbas.EEB44AC1 |
قاعدة البيانات: | BASE |
DOI: | 10.1128/aem.01993-18 |
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