Academic Journal
奈良県の高齢化地域におけるボノプラザンを用いたヘリコバクター・ピロリ除菌に関する検討 ; A Study on Vonoprazan Based Helicobacter Pylori Eradication with in An Aging Community in Nara Prefecture.
| العنوان: | 奈良県の高齢化地域におけるボノプラザンを用いたヘリコバクター・ピロリ除菌に関する検討 ; A Study on Vonoprazan Based Helicobacter Pylori Eradication with in An Aging Community in Nara Prefecture. |
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| المؤلفون: | 瓦谷, 英人, 久保, 卓也, 簗瀬, 公嗣, 藤本, 優樹, 中上, 純子, 小林, 正尚, 丸山, 直樹, 前川, 勝英, 松倉, 康夫, 松島, 俊裕, 吉治, 仁志, 西尾, 健治 |
| بيانات النشر: | 奈良医学会 奈良県立医科大学 |
| سنة النشر: | 2021 |
| المجموعة: | Nara Medical University: GINMU - Global Institutional Repository / 奈良県立医科大学機関リポジトリ |
| مصطلحات موضوعية: | Helicobacter pylori, Eradication, Elderly people |
| الوصف: | Introduction: There are few reports on the efficacy and safety of vonoprazan (P-CAB) based triple eradication therapy in the elderly. In this study, we investigated the efficacy and safety of P-CAB based eradication of Helicobacter pylori (H. pylori) in non-elderly and elderly patients in our community, where the elderly population is high (41.7%). Methods: 205 patients who underwent primary and secondary eradication for H. pylori at our hospital from October 2018 to December 2020, were included in this study. Results: In primary eradication, the success rate for eradication in non-elderly and elderly patients was 96.6% (57 of 59 patients) and 88.7% (110 of 124 patients) respectively (P=0.10). The success rate for eradication in the late-elderly was 90.2% (46 of 51 patients). There was no significant difference compared with non-elderly patients (P = 0.25). The success rates for secondary eradication in non-elderly and elderly patients were 100% (7 of 7 patients) and 66.7% (10 of 15 patients). respectively, with no significant difference between the two groups (P = 0.13). The success rate for eradication in the late-elderly was low (40.0%: 2 of 5 cases). and there was significant difference compared with that in the non-elderly (P < 0.05). In the primary eradication, there was only one case of death from other diseases in the late-elderly patients during the first week after treatment. Discussion: In the elderly, the efficacy of primary eradication was similar to that for the non-elderly, and the frequency of incidental disease was low. Although the efficacy of secondary eradication was lower in the elderly, it was a safe treatment. |
| نوع الوثيقة: | article in journal/newspaper report |
| اللغة: | Japanese |
| تدمد: | 13450069 |
| Relation: | Journal of Nara Medical Association Vol.72 No.4,5,6 p.29-33 (2021.11); http://hdl.handle.net/10564/4034; AA11252383; Journal of Nara Medical Association; 72; 4,5,6; 29; 33 |
| الاتاحة: | http://hdl.handle.net/10564/4034 |
| Rights: | publisher |
| رقم الانضمام: | edsbas.EE2DA112 |
| قاعدة البيانات: | BASE |
| تدمد: | 13450069 |
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