التفاصيل البيبلوغرافية
| العنوان: |
Characterizing a lethal mitonuclear incompatibility in naturally hybridizing Xiphophorus swordtails |
| المؤلفون: |
Moran, Benjamin, Payne, Cheyenne, Powell, Daniel, Iverson, Erik, Donny, Alex, Banerjee, Shreya, Langdon, Quinn, Gunn, Theresa, Rodriguez-Soto, Rebecca, Madero, Angel, Baczenas, John, Kleczko, Korbin, Liu, Fang, Matney, Rowan, Singhal, Kratika, Leib, Ryan, Hernandez-Perez, Osvaldo, Corbett-Detig, Russell, Frydman, Judith, Gifford, Casey, Schartl, Manfred, Havird, Justin, Schumer, Molly |
| بيانات النشر: |
Zenodo |
| سنة النشر: |
2023 |
| المجموعة: |
Zenodo |
| مصطلحات موضوعية: |
Xiphophorus, malinche, birchmanni, cortezi, Respirometry, Mitochondrial genetics, Oxidative phosphorylation, Protein structure, Proteomics, Gene mapping, Epistasis, Evolutionary rate, Coevolution, Histology, Flow cytometry, Sequence alignment |
| الوصف: |
The evolution of reproductive barriers is the first step in the formation of new species and can help us understand the diversification of life on Earth. These reproductive barriers often take the form of "hybrid incompatibilities," where alleles derived from two different species no longer interact properly in hybrids . Theory predicts that hybrid incompatibilities may be more likely to arise at rapidly evolving genes and that incompatibilities involving multiple genes should be common , but there has been sparse empirical data to evaluate these predictions. Here, we describe a mitonuclear incompatibility involving three genes in physical contact within respiratory Complex I of naturally hybridizing swordtail fish species. Individuals homozygous for mismatched protein combinations fail to complete embryonic development or die as juveniles, while those heterozygous for the incompatibility have reduced Complex I function and unbalanced representation of parental alleles in the mitochondrial proteome. We find that the impacts of different genetic interactions on survival are non-additive, highlighting subtle complexity in the genetic architecture of hybrid incompatibilities. Finally, we document the evolutionary history of the genes involved, showing signals of accelerated evolution and the first case of an incompatibility transferred between species via hybridization. ; Funding provided by: National Science Foundation Crossref Funder Registry ID: https://ror.org/021nxhr62 Award Number: 2019273798 Funding provided by: National Science Foundation Crossref Funder Registry ID: https://ror.org/021nxhr62 Award Number: 2010950 Funding provided by: National Cancer Institute Crossref Funder Registry ID: https://ror.org/040gcmg81 Award Number: CA124435 Funding provided by: National Institute of General Medical Sciences Crossref Funder Registry ID: https://ror.org/04q48ey07 Award Number: 1R35GM142836 Funding provided by: National Institute of General Medical Sciences Crossref Funder Registry ID: https://ror.org/04q48ey07 ... |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
unknown |
| Relation: |
https://doi.org/10.1101/2021.07.13.452279; https://zenodo.org/communities/dryad; https://doi.org/10.5061/dryad.j3tx95xmx; oai:zenodo.org:10160341 |
| DOI: |
10.5061/dryad.j3tx95xmx |
| الاتاحة: |
https://doi.org/10.5061/dryad.j3tx95xmx |
| Rights: |
info:eu-repo/semantics/openAccess ; Creative Commons Zero v1.0 Universal ; https://creativecommons.org/publicdomain/zero/1.0/legalcode |
| رقم الانضمام: |
edsbas.EDE29A |
| قاعدة البيانات: |
BASE |