Treatment patterns and outcomes among nontransplant newly diagnosed multiple myeloma patients in Spain

التفاصيل البيبلوغرافية
العنوان: Treatment patterns and outcomes among nontransplant newly diagnosed multiple myeloma patients in Spain
المؤلفون: Hernández-Rivas, J.-A., Arnao, M., Arguiñano Pérez, J.M., Rubio, A., González García, E., De Miguel, D., Cherepanov, D., Romanus, D., Verleger, K., Johnson, C., Corman, S.L., Grande, M., Pérez Persona, E.
سنة النشر: 2021
المجموعة: Digital Repository of University of Zaragoza (ZAGUAN)
الوصف: Aim: To describe treatment patterns and outcomes in nontransplant newly diagnosed multiple myeloma (NDMM) patients in Spain. Methods: This retrospective study included two cohorts of NDMM patients diagnosed between 1 January 2012 to 31 December 2013 and 1 April 2016 to 31 March 2017. Results: Among 113 patients, proteasome inhibitor (PI) + alkylator combinations (49%) and PI-based regimens without an alkylator (30%) were the most common first-line (1L) therapies. Use of PI + immunomodulatory drug-based regimens increased between the cohorts; PI-based regimens without an alkylator/immunomodulatory drug decreased. Use of 1L oral regimens was low but increased over time; use of maintenance therapy was low across both periods. Median 1L duration of treatment was 6.9 months. Conclusion: Short 1L duration of treatment and low use of 1L oral regimens and maintenance therapy highlight unmet needs in NDMM. © 2021 The Authors.
نوع الوثيقة: conference object
وصف الملف: application/pdf
اللغة: English
Relation: http://zaguan.unizar.es/record/112744
DOI: 10.2217/fon-2021-0301
الاتاحة: http://zaguan.unizar.es/record/112744
https://doi.org/10.2217/fon-2021-0301
Rights: by-nc-nd ; http://creativecommons.org/licenses/by-nc-nd/3.0/es/
رقم الانضمام: edsbas.ED1B862C
قاعدة البيانات: BASE